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硫胺素缺乏作为可逆性肺源性心脏病的一个病因

Thiamin deficiency as a cause of reversible cor pulmonale.

作者信息

Coelho Liana S, Hueb João C, Minicucci Marcos F, Azevedo Paula S, Paiva Sergio A R, Zornoff Leonardo A M

机构信息

Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brasil.

出版信息

Arq Bras Cardiol. 2008 Jul;91(1):e7-9. doi: 10.1590/s0066-782x2008001300013.

DOI:10.1590/s0066-782x2008001300013
PMID:18660937
Abstract

Thiamine deficiency may present four classic clinical forms: peripheral polyneuropathy, anorexia and muscular weakness (dry beriberi); high output heart failure with signs of congestion (wet beriberi); beriberi associated with shock (Shoshin beriberi) and Wernicke's encephalopathy. In this report we describe a picture that is suggestive of severe pulmonary hypertension and cor pulmonale, with jugular stasis, congestive hepatitis and generalized edema that reversed completely after the administration of thiamine.

摘要

硫胺素缺乏可能呈现四种典型临床形式

周围性多发性神经病、厌食和肌肉无力(干性脚气病);伴有充血体征的高输出量心力衰竭(湿性脚气病);与休克相关的脚气病(急性暴发性脚气病)和韦尼克脑病。在本报告中,我们描述了一幅提示严重肺动脉高压和肺心病的图景,伴有颈静脉瘀血、充血性肝炎和全身性水肿,在给予硫胺素后完全逆转。

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