Kampinga Harm H, Hageman Jurre, Vos Michel J, Kubota Hiroshi, Tanguay Robert M, Bruford Elspeth A, Cheetham Michael E, Chen Bin, Hightower Lawrence E
Department of Cell Biology, Section of Radiation and Stress Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Cell Stress Chaperones. 2009 Jan;14(1):105-11. doi: 10.1007/s12192-008-0068-7. Epub 2008 Jul 29.
The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines for the nomenclature of the human HSP families, HSPH (HSP110), HSPC (HSP90), HSPA (HSP70), DNAJ (HSP40), and HSPB (small HSP) as well as for the human chaperonin families HSPD/E (HSP60/HSP10) and CCT (TRiC). The nomenclature is based largely on the more consistent nomenclature assigned by the HUGO Gene Nomenclature Committee and used in the National Center of Biotechnology Information Entrez Gene database for the heat shock genes. In addition to this nomenclature, we provide a list of the human Entrez Gene IDs and the corresponding Entrez Gene IDs for the mouse orthologs.
人类各种热休克蛋白（HSP）家族成员数量不断增加，且其命名存在不一致性，这常常导致混淆。在此，我们提出人类HSP家族（HSPH（HSP110）、HSPC（HSP90）、HSPA（HSP70）、DNAJ（HSP40）和HSPB（小HSP））以及人类伴侣蛋白家族HSPD/E（HSP60/HSP10）和CCT（TRiC）命名的新指南。该命名主要基于人类基因组组织基因命名委员会指定的、并在国家生物技术信息中心基因数据库中用于热休克基因的更一致的命名。除了这个命名法，我们还提供了人类Entrez基因ID列表以及小鼠直系同源基因对应的Entrez基因ID。
