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澳大利亚男性队列中的慢性病患病率及关联:弗洛里阿德莱德男性衰老研究(FAMAS)

Chronic disease prevalence and associations in a cohort of Australian men: the Florey Adelaide Male Ageing Study (FAMAS).

作者信息

Martin Sean A, Haren Matthew T, Taylor Anne W, Middleton Sue M, Wittert Gary A

机构信息

Discipline of Medicine, Freemasons Foundation Centre for Men's Health, University of Adelaide, Adelaide, SA, 5000, Australia.

出版信息

BMC Public Health. 2008 Jul 30;8:261. doi: 10.1186/1471-2458-8-261.

Abstract

BACKGROUND

An increasing proportion of Australia's chronic disease burden is carried by the ageing male. The aim of this study was to determine the prevalence of asthma, cancer, diabetes, angina and musculoskeletal conditions and their relationship to behavioural and socio-demographic factors in a cohort of Australian men.

METHODS

Self-reports of disease status were obtained from baseline clinic visits (August 2002-July 2003 & July 2004-May 2005) from 1195 randomly selected men, aged 35-80 years and living in the north-west regions of Adelaide. Initially, relative risks were assessed by regression against selected variables for each outcome. Where age-independent associations were observed with the relevant chronic disease, independent variables were fitted to customized multiadjusted models.

RESULTS

The prevalence of all conditions was moderately higher in comparison to national data for age-matched men. In particular, there was an unusually high rate of men with cancer. Multiadjusted analyses revealed age as a predictor of chronic conditions (type 2 diabetes mellitus, angina, cancer & osteoarthritis). A number of socio-demographic factors, independent of age, were associated with chronic disease, including: low income status (diabetes), separation/divorce (asthma), unemployment (cancer), high waist circumference (diabetes), elevated cholesterol (angina) and a family history of obesity (angina).

CONCLUSION

Socio-demographic factors interact to determine disease status in this broadly representative group of Australian men. In addition to obesity and a positive personal and family history of disease, men who are socially disadvantaged (low income, unemployed, separated) should be specifically targeted by public health initiatives.

摘要

背景

澳大利亚慢性病负担中,老年男性所占比例日益增加。本研究旨在确定澳大利亚一组男性队列中哮喘、癌症、糖尿病、心绞痛和肌肉骨骼疾病的患病率及其与行为和社会人口学因素的关系。

方法

从1195名年龄在35 - 80岁、居住在阿德莱德西北地区的随机选取男性的基线门诊就诊记录(2002年8月 - 2003年7月及2004年7月 - 2005年5月)中获取疾病状况的自我报告。最初,通过对每个结局的选定变量进行回归分析来评估相对风险。当观察到与相关慢性病存在年龄无关的关联时,将自变量纳入定制的多重调整模型。

结果

与年龄匹配男性的全国数据相比,所有疾病的患病率均略高。特别是,患癌症的男性比例异常高。多重调整分析显示年龄是慢性病(2型糖尿病、心绞痛、癌症和骨关节炎)的一个预测因素。一些与年龄无关的社会人口学因素与慢性病相关,包括:低收入状况(糖尿病)、分居/离婚(哮喘)、失业(癌症)、高腰围(糖尿病)、胆固醇升高(心绞痛)和肥胖家族史(心绞痛)。

结论

在这个具有广泛代表性的澳大利亚男性群体中,社会人口学因素相互作用以决定疾病状况。除了肥胖以及个人和家族疾病史呈阳性外,社会处境不利(低收入、失业、分居)的男性应成为公共卫生举措的特定目标人群。

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