Mudd Lanay M, Pham Xinh, Nechuta Sarah, Elliott Michael R, Lepkowski James M, Paneth Nigel
Department of Epidemiology, Michigan State University, B601 West Fee Hall, East Lansing, MI 48824, USA.
Matern Child Health J. 2008 Nov;12(6):684-91. doi: 10.1007/s10995-008-0393-6. Epub 2008 Jul 31.
The cooperation of healthcare personnel is essential for implementing clinical research, yet little is known about the willingness of staff to facilitate research. This study assessed attitudes of prenatal clinic and delivery room (DR) staff toward facilitation of research, with a particular focus on the National Children's Study (NCS).
Staff from seven sampled prenatal clinics (N=82) and all three DRs in Kent County, MI (N=169) completed anonymous surveys assessing willingness to recruit patients (clinic) or collect biological specimens (DR), desired incentives, and barriers to research in general and the NCS specifically.
Clinic staff included 36 office workers, 29 nurses, 11 medical assistants and 6 physicians/physician assistants. DR staff included 127 nurses, 19 support staff, 11 physicians and 10 technicians. Clinic staff would hand out brochures (72%) and describe studies (65%), but only 44% wanted outside research staff to recruit patients. Non-White staff were 4.1 times more likely (95% CI. 1.2-14.1) to permit outside staff to recruit. DR staff would collect placentas (84%) and cord blood (77%), and preferred DR staff to perform the collections. In both settings, financial incentives were not required or were modest. Lack of time was the most reported research barrier, followed by patient flow and lack of space. A small fraction of healthcare workers reported refusal to facilitate research tasks.
Careful planning of research with all clinic and DR staff will be necessary for successful execution of the NCS or other large-scale clinical research studies.
医护人员的合作对于开展临床研究至关重要，但对于工作人员协助研究的意愿却知之甚少。本研究评估了产前诊所和产房（DR）工作人员对协助研究的态度，特别关注了国家儿童研究（NCS）。
来自密歇根州肯特县七家抽样产前诊所（N = 82）和所有三家产房（N = 169）的工作人员完成了匿名调查，评估招募患者（诊所）或收集生物标本（产房）的意愿、期望的激励措施以及一般研究和NCS研究的障碍。
诊所工作人员包括36名办公室工作人员、29名护士、11名医疗助理和6名医生/医师助理。产房工作人员包括127名护士、19名辅助人员、11名医生和10名技术人员。诊所工作人员会分发宣传册（72%）并描述研究（65%），但只有44%希望外部研究人员招募患者。非白人工作人员允许外部人员招募的可能性高4.1倍（95%可信区间：1.2 - 14.1）。产房工作人员会收集胎盘（84%）和脐带血（77%），并更倾向于由产房工作人员进行采集。在这两种情况下，都不需要或只需适度的经济激励。报告最多的研究障碍是时间不足，其次是患者流量和空间不足。一小部分医护人员报告拒绝协助研究任务。
要成功实施NCS或其他大规模临床研究，必须与所有诊所和产房工作人员精心规划研究。
