Tibazarwa K B, Volmink J A, Mayosi B M
Department of Medicine, J Floor Old Main Building, Groote Schuur Hospital, Cape Town, South Africa.
Heart. 2008 Dec;94(12):1534-40. doi: 10.1136/hrt.2007.141309. Epub 2008 Jul 31.
There is no systematic overview of prospective studies of incidence of acute rheumatic fever (ARF) in the world.
To summarise all population-based studies of the incidence of ARF world wide.
A systematic review of prospective population-based studies of the overall mean and annual specific incidence of the first episode of ARF was carried out.
A systematic literature search identified 10 eligible studies from 10 countries on all continents, except Africa. The overall mean incidence rate of first attack of ARF was 5-51/100,000 population (mean 19/100,000; 95% CI 9 to 30/100,000). A low incidence rate of <or=10/100,000 per year was found in America and Western Europe, while a higher incidence (>10/100,000) was documented in Eastern Europe, Middle East (highest), Asia and Australasia. Studies with longitudinal data displayed a falling incidence rate over time.
Despite an apparent fall in incidence over time, ARF incidence rates remain relatively high in non-Western countries. No information is available for Africa.
目前尚无关于全球急性风湿热（ARF）发病率前瞻性研究的系统综述。
总结全球范围内所有基于人群的ARF发病率研究。
对基于人群的ARF首次发作总体平均发病率和年度特定发病率的前瞻性研究进行系统综述。
系统文献检索确定了除非洲外各大洲10个国家的10项符合条件的研究。ARF首次发作的总体平均发病率为5 - 51/10万人口（平均19/10万；95%置信区间9至30/10万）。美洲和西欧每年发病率<或=10/10万，而东欧、中东（最高）、亚洲和澳大拉西亚的发病率较高（>10/10万）。有纵向数据的研究显示发病率随时间下降。
尽管发病率随时间明显下降，但在非西方国家ARF发病率仍然相对较高。非洲尚无相关信息。
