Eickmann Sophie H, Brito Cristiana M M, Lira Pedro I C, Lima Marilia C
Departamento Materno Infantil, Universidade Federal de Pernambuco, Recife, Brasil.
Cad Saude Publica. 2008;24 Suppl 2:S303-11. doi: 10.1590/s0102-311x2008001400015.
This study analyzed the effectiveness of weekly iron supplementation on hemoglobin concentration, nutritional status, and mental and motor development of infants at four public daycare centers in Recife, Pernambuco State, Brazil. This was a before-after intervention study conducted with weekly iron supplementation for six months in a sample of 76 infants in the 4 to 24 month age group, from February to December 2005. Mental and motor development was assessed through the Bayley Scale of Infant Development II. After supplementation, a significant increase was observed in hemoglobin concentration in the group of infants with initial hemoglobin level < or = 9.5g/dL (p = 0.001). There was also a significant increase in the mean weight-for-length z-score, but the opposite was found for length-for-age. No difference was observed in the developmental indices. We conclude that weekly iron supplementation was effective for increasing hemoglobin concentration in infants with lower initial levels, but no impact on infant development was observed.
本研究分析了在巴西伯南布哥州累西腓的四个公共日托中心，每周补充铁剂对婴儿血红蛋白浓度、营养状况以及心理和运动发育的效果。这是一项前后干预研究，于2005年2月至12月，对4至24个月龄的76名婴儿样本进行了为期六个月的每周铁剂补充。通过贝利婴儿发展量表第二版评估心理和运动发育。补充后，初始血红蛋白水平≤9.5g/dL的婴儿组血红蛋白浓度显著增加（p = 0.001）。平均身长体重z评分也显著增加，但年龄身长却相反。在发育指标上未观察到差异。我们得出结论，每周补充铁剂对提高初始水平较低的婴儿的血红蛋白浓度有效，但未观察到对婴儿发育有影响。
