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Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.

作者信息

Dashwood Roderick H, Ho Emily

机构信息

The Linus Pauling Institute, Department of Environmental and Molecular Toxicology, and Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, Oregon 97331, USA.

出版信息

Nutr Rev. 2008 Aug;66 Suppl 1(Suppl 1):S36-8. doi: 10.1111/j.1753-4887.2008.00065.x.

DOI:10.1111/j.1753-4887.2008.00065.x
PMID:18673487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2656672/
Abstract
摘要

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本文引用的文献

1
Histone deacetylase inhibitors: molecular mechanisms of action.组蛋白去乙酰化酶抑制剂：作用的分子机制
Oncogene. 2007 Aug 13;26(37):5541-52. doi: 10.1038/sj.onc.1210620.
2
Dietary histone deacetylase inhibitors: from cells to mice to man.饮食中的组蛋白去乙酰化酶抑制剂：从细胞到小鼠再到人类
Semin Cancer Biol. 2007 Oct;17(5):363-9. doi: 10.1016/j.semcancer.2007.04.001. Epub 2007 May 5.
3
Molecular basis for chemoprevention by sulforaphane: a comprehensive review.萝卜硫素化学预防的分子基础：综述
Cell Mol Life Sci. 2007 May;64(9):1105-27. doi: 10.1007/s00018-007-6484-5.
4
Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines.萝卜硫素在人乳腺癌细胞系中诱导细胞类型特异性凋亡。
Mol Cancer Ther. 2007 Mar;6(3):1013-21. doi: 10.1158/1535-7163.MCT-06-0494. Epub 2007 Mar 5.
5
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.萝卜硫素可延缓人PC-3异种移植瘤的生长，并抑制人体中的组蛋白去乙酰化酶活性。
Exp Biol Med (Maywood). 2007 Feb;232(2):227-34.
6
Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells.苯己基异硫氰酸酯抑制组蛋白脱乙酰酶并重塑染色质，从而诱导人白血病细胞生长停滞。
Int J Oncol. 2006 May;28(5):1287-93.
7
Chemoprotection by sulforaphane: keep one eye beyond Keap1.萝卜硫素的化学保护作用：超越Keap1，放眼其他方面。
Cancer Lett. 2006 Feb 28;233(2):208-18. doi: 10.1016/j.canlet.2005.02.033.
8
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.萝卜硫素在体内可抑制组蛋白脱乙酰基酶，并抑制Apc基因缺失小鼠的肿瘤发生。
FASEB J. 2006 Mar;20(3):506-8. doi: 10.1096/fj.05-4785fje. Epub 2006 Jan 11.
9
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.萝卜硫素抑制BPH-1、LnCaP和PC-3前列腺上皮细胞中的组蛋白脱乙酰酶活性。
Carcinogenesis. 2006 Apr;27(4):811-9. doi: 10.1093/carcin/bgi265. Epub 2005 Nov 9.
10
Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?饮食中的组蛋白去乙酰化酶抑制剂：是时候重新思考癌症化学预防中的弱配体了吗？
Carcinogenesis. 2006 Feb;27(2):344-9. doi: 10.1093/carcin/bgi253. Epub 2005 Nov 2.