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Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.

作者信息

Dashwood Roderick H, Ho Emily

机构信息

The Linus Pauling Institute, Department of Environmental and Molecular Toxicology, and Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, Oregon 97331, USA.

出版信息

Nutr Rev. 2008 Aug;66 Suppl 1(Suppl 1):S36-8. doi: 10.1111/j.1753-4887.2008.00065.x.

Abstract
摘要

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本文引用的文献

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Histone deacetylase inhibitors: molecular mechanisms of action.
Oncogene. 2007 Aug 13;26(37):5541-52. doi: 10.1038/sj.onc.1210620.
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Dietary histone deacetylase inhibitors: from cells to mice to man.
Semin Cancer Biol. 2007 Oct;17(5):363-9. doi: 10.1016/j.semcancer.2007.04.001. Epub 2007 May 5.
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Molecular basis for chemoprevention by sulforaphane: a comprehensive review.
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Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines.
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Chemoprotection by sulforaphane: keep one eye beyond Keap1.
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Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
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Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
Carcinogenesis. 2006 Apr;27(4):811-9. doi: 10.1093/carcin/bgi265. Epub 2005 Nov 9.
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Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?
Carcinogenesis. 2006 Feb;27(2):344-9. doi: 10.1093/carcin/bgi253. Epub 2005 Nov 2.

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