Bryson Susan E, Bradley Elspeth A, Thompson Ann, Wainwright Ann
Department of Pediatrics, Dalhousie University-IWK Health Centre, Halifax, Nova Scotia.
Can J Psychiatry. 2008 Jul;53(7):449-59. doi: 10.1177/070674370805300710.
To estimate the prevalence of autism in an epidemiologically-derived population of adolescents with intellectual disabilities (ID).
The prevalence of autism was examined using the Autism Diagnostic Interview-Revised, with appropriate care taken in assessing lower functioning individuals and those with additional physical and sensory impairments. Individual assessment during psychological evaluation, and consensus classification of complex cases, involving clinicians experienced in the assessment of autism, contributed to the identification of autism.
Overall, 28% of individuals, or 2.0 of the 7.1/1000 with ID in the target population (as we have previously identified in another study), were identified with autism. Autism rates did not differ significantly across severe ID (32.0%) and mild ID (24.1%); males predominated (2.3 males to 1 female), but less so for severe ID (2 males to 1 female, compared with 2.8 males to 1 female for mild ID). Socioeconomic status did not distinguish the groups with and without autism. Less than one-half of the adolescents who met diagnostic criteria for autism were previously diagnosed as such.
Our overall prevalence estimate for autism is in the higher range of estimates reported in previous studies of ID (more so for mild ID). This likely reflects the changes in diagnostic criteria for autism that have subsequently occurred. Discussion focuses on the identification of autism in the population with ID, and on the implications for service delivery and clinical training.
评估在源自流行病学的智障青少年人群中自闭症的患病率。
采用修订版自闭症诊断访谈来检查自闭症的患病率,在评估功能较低的个体以及那些有其他身体和感官障碍的个体时采取了适当的措施。心理评估期间的个体评估以及涉及自闭症评估经验丰富的临床医生对复杂病例的共识分类,有助于自闭症的识别。
总体而言,目标人群中28%的个体,即每1000名智障者中有2.0名(正如我们之前在另一项研究中所确定的)被诊断为自闭症。自闭症患病率在重度智障者(32.0%)和轻度智障者(24.1%)之间没有显著差异;男性占主导(男性与女性比例为2.3:1),但在重度智障者中比例较低(男性与女性比例为2:1,而轻度智障者为2.8:1)。社会经济地位并不能区分有无自闭症的群体。符合自闭症诊断标准的青少年中,不到一半之前被诊断为此病。
我们对自闭症总体患病率的估计处于先前智障研究报告的较高范围(轻度智障者更是如此)。这可能反映了随后自闭症诊断标准的变化。讨论集中在智障人群中自闭症的识别以及对服务提供和临床培训的影响。