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膳食苯并[a]芘对许氏平鲉幼鱼生长和血液学参数的影响

Effects of dietary benzo[a]pyrene on growth and hematological parameters in juvenile rockfish, Sebastes schlegeli (Hilgendorf).

作者信息

Kim Seong Gil, Park Dae Kuk, Jang Suck Woo, Lee Jae Seong, Kim Seong Soo, Chung Mi Hee

机构信息

Marine Environmental Management Team, National Fisheries Research and Development Institute, Busan 619-902, South Korea.

出版信息

Bull Environ Contam Toxicol. 2008 Nov;81(5):470-4. doi: 10.1007/s00128-008-9499-1. Epub 2008 Aug 2.

DOI:10.1007/s00128-008-9499-1
PMID:18677433
Abstract

Experiments were conducted to evaluate the effect of dietary benzo[a]pyrene (B[a]P) on the growth and hematological parameters of rockfish, Sebastes schlegeli, after they were fed with subchronic dietary B[a]P for 30 days. The weight growth rate of the rockfish was significantly different from that of the control group at dietary B[a]P concentration of 1.5 and 2.0 mg/kg. Significant reduction in red blood cells, hematocrit, and hemoglobin were observed during 30 days of exposure to the highest concentration. Over 30 days, serum AST increased at a B[a]P concentration of 1.5 mg/kg and LDH increased at a B[a]P concentration of 1.0 mg/kg concentration. However, no changes were observed in ALT, total protein, magnesium or calcium.

摘要

进行了实验,以评估在将岩鱼(许氏平鲉)用亚慢性膳食苯并[a]芘(B[a]P)喂养30天后,膳食中苯并[a]芘(B[a]P)对其生长和血液学参数的影响。在膳食B[a]P浓度为1.5和2.0 mg/kg时,岩鱼的体重增长率与对照组有显著差异。在暴露于最高浓度的30天内,观察到红细胞、血细胞比容和血红蛋白显著减少。在30天内,血清AST在B[a]P浓度为1.5 mg/kg时升高,LDH在B[a]P浓度为1.0 mg/kg时升高。然而,ALT、总蛋白、镁或钙没有变化。

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