Kim Jun-Hwan, Kang Ju-Chan
Department of Aquatic Life Medicine, Pukyong National University, Busan 608-737, Republic of Korea.
Department of Aquatic Life Medicine, Pukyong National University, Busan 608-737, Republic of Korea.
Ecotoxicol Environ Saf. 2015 May;115:33-9. doi: 10.1016/j.ecoenv.2015.02.009. Epub 2015 Feb 10.
Juvenile rockfish (mean length 14.2 ± 1.9 cm, and mean weight 57.3 ± 5.2g) were exposed for 4 weeks with the different levels of dietary lead (Pb(2+)) at 0, 30, 60, 120 and 240 mg/L. The exposure concentration and period of Pb have induced significant amount of it the specific tissues of rockfish. The highest Pb accumulation was observed in the kidney tissue by the dietary lead exposure. The growth rate and hepatosomatic index were considerably inhibited over 120 mg/kg. The hematological parameters such as red blood cell (RBC) counts, hematocrit (Ht) value, and hemoglobin (Hb) concentration were significantly decreased over 60 mg/kg Pb concentration. In the inorganic components, the values of calcium and magnesium in plasma were significantly decreased. The glucose and cholesterol values were notably increased, whereas total protein was decreased. The enzyme components, glutamic oxalate transaminase (GOT) and glutamic pyruvate transaminase (GPT), were significantly elevated by the dietary lead exposure, but no change was observed in alkaline phosphatase (ALP).
将平均体长14.2±1.9厘米、平均体重57.3±5.2克的幼龄岩鱼，暴露于浓度分别为0、30、60、120和240毫克/升的不同水平膳食铅（Pb(2+)）中4周。铅的暴露浓度和时间在岩鱼的特定组织中诱导出了大量铅。通过膳食铅暴露，在肾脏组织中观察到最高的铅蓄积量。超过120毫克/千克时，生长速率和肝体指数受到显著抑制。超过60毫克/千克的铅浓度时，红细胞计数、血细胞比容值和血红蛋白浓度等血液学参数显著降低。在无机成分方面，血浆中的钙和镁值显著降低。葡萄糖和胆固醇值显著升高，而总蛋白降低。膳食铅暴露使酶成分谷氨酸草酰乙酸转氨酶（GOT）和谷氨酸丙酮酸转氨酶（GPT）显著升高，但碱性磷酸酶（ALP）未观察到变化。
