Kim Jun-Hwan, Kang Ju-Chan
West Sea Fisheries Research Institute, National Institute of Fisheries Science, Incheon 22383, South Korea.
Department of Aquatic Life Medicine, Pukyong National University, Busan 48513, South Korea.
Chemosphere. 2017 Jun;176:131-140. doi: 10.1016/j.chemosphere.2017.02.097. Epub 2017 Feb 20.
Juvenile rockfish, Sebastes schlegelii (mean length 11.3 ± 1.2 cm, and mean weight 32.5 ± 4.1 g) were exposed for four weeks to dietary lead (Pb) at 0, 120, and 240 mg/L and ascorbic acid (AsA) at 100, 200, and 400 mg/L. The exposure concentrations and duration of significant Pb-induced accumulations in specific tissues of S. schlegelii were assessed. High levels of ascorbic acid significantly attenuated accumulations following exposure to dietary Pb. Dietary Pb exposure caused a significant increase in blood Pb concentrations, whereas red blood cell (RBC) count, hematocrit, and hemoglobin were significantly decreased. Notable changes were also observed in plasma calcium, magnesium, glucose, cholesterol, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvate transaminase (GPT). The growth performance of S. schlegelii was significantly decreased. High doses AsA supplemention were effective in attenuating the changes brought about by dietary Pb exposure.
将平均体长为11.3±1.2厘米、平均体重为32.5±4.1克的许氏平鲉幼鱼，分别暴露于铅（Pb）含量为0、120和240毫克/升以及抗坏血酸（AsA）含量为100、200和400毫克/升的饲料中四周。评估了许氏平鲉特定组织中铅诱导显著积累的暴露浓度和持续时间。高含量的抗坏血酸显著减弱了饲料铅暴露后的积累。饲料铅暴露导致血液铅浓度显著升高，而红细胞（RBC）计数、血细胞比容和血红蛋白显著降低。血浆钙、镁、葡萄糖、胆固醇、谷草转氨酶（GOT）和谷丙转氨酶（GPT）也出现了显著变化。许氏平鲉的生长性能显著下降。高剂量补充抗坏血酸能有效减轻饲料铅暴露带来的变化。
