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比较传统痔切除术与LigaSure治疗痔疮的随机对照试验的更新荟萃分析。

Updated meta-analysis of randomized controlled trials comparing conventional excisional haemorrhoidectomy with LigaSure for haemorrhoids.

作者信息

Mastakov M Y, Buettner P G, Ho Y-H

机构信息

Department of Surgery School of Medicine, James Cook University, The Townsville Hospital, Townsville, Queensland 4814, Australia.

出版信息

Tech Coloproctol. 2008 Sep;12(3):229-39. doi: 10.1007/s10151-008-0426-6. Epub 2008 Aug 5.

DOI:10.1007/s10151-008-0426-6
PMID:18679571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2799011/
Abstract

BACKGROUND

To compare the surgical outcome of haemorrhoidectomy performed using LigaSure bipolar diathermy with conventional haemorrhoidectomy.

METHODS

Only randomized and alternate allocated studies were included from the major electronic databases using the search terms "ligasure" and "haemorrhoids". Duration of operation, blood loss during operation, postoperative pain score, wound healing, in-hospital stay, time to return to normal activities and complications were assessed.

RESULTS

The 11 trials contained a total of 1,046 patients; the largest study was based on 273 patients and two earlier studies were based on 34 patients. No significant gender mismatch between the groups was reported in any of the studies. The patients' ages were similar between groups in the studies, as was disease severity. All 11 studies reported a shorter duration of the operation when using LigaSure compared to the conventional technique (p<0.001). The postoperative pain score (p=0.001) and blood loss during operation (p=0.001) were significantly reduced. After LigaSure haemorrhoidectomy wound healing (p=0.004) and the return to normal activities (p=0.001) were significantly faster than after conventional haemorrhoidectomy. However, the overall incidence of complications reported was not significantly different (p=0.056).

CONCLUSIONS

LigaSure is an effective instrument for haemorrhoidectomy which results in less blood loss, quicker wound healing and earlier return to work.

摘要

背景

比较使用LigaSure双极电凝进行痔切除术与传统痔切除术的手术效果。

方法

从主要电子数据库中仅纳入使用搜索词“LigaSure”和“痔疮”的随机及交替分配研究。评估手术时间、术中失血、术后疼痛评分、伤口愈合情况、住院时间、恢复正常活动时间及并发症。

结果

11项试验共纳入1046例患者;最大的研究基于273例患者,两项早期研究基于34例患者。所有研究均未报告组间存在显著性别差异。各研究中组间患者年龄及疾病严重程度相似。所有11项研究均报告,与传统技术相比,使用LigaSure时手术时间更短(p<0.001)。术后疼痛评分(p=0.001)及术中失血(p=0.001)显著降低。LigaSure痔切除术后伤口愈合(p=0.004)及恢复正常活动(p=0.001)明显快于传统痔切除术后。然而,报告的总体并发症发生率无显著差异(p=0.056)。

结论

LigaSure是一种有效的痔切除器械,可减少失血、加快伤口愈合并更早恢复工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/858e7fd74c0b/10151_2008_Article_426_Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/c0af000f5879/10151_2008_Article_426_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/58f969900c5c/10151_2008_Article_426_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/9ff4be7dadd6/10151_2008_Article_426_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/bee961101694/10151_2008_Article_426_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/858e7fd74c0b/10151_2008_Article_426_Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/c0af000f5879/10151_2008_Article_426_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/58f969900c5c/10151_2008_Article_426_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/9ff4be7dadd6/10151_2008_Article_426_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/bee961101694/10151_2008_Article_426_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3b9/2799011/858e7fd74c0b/10151_2008_Article_426_Fig5.jpg

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