2007年密克罗尼西亚联邦雅浦州寨卡病毒流行的遗传与血清学特性

Lanciotti Robert S, Kosoy Olga L, Laven Janeen J, Velez Jason O, Lambert Amy J, Johnson Alison J, Stanfield Stephanie M, Duffy Mark R

Diagnostic and Reference Laboratory, Arbovirus Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521, USA.

Emerg Infect Dis. 2008 Aug;14(8):1232-9. doi: 10.3201/eid1408.080287.

Zika virus (ZIKV) is a mosquito-borne flavivirus first isolated in Uganda from a sentinel monkey in 1947. Mosquito and sentinel animal surveillance studies have demonstrated that ZIKV is endemic to Africa and Southeast Asia, yet reported human cases are rare, with <10 cases reported in the literature. In June 2007, an epidemic of fever and rash associated with ZIKV was detected in Yap State, Federated States of Micronesia. We report the genetic and serologic properties of the ZIKV associated with this epidemic.

寨卡病毒（ZIKV）是一种由蚊子传播的黄病毒，1947年首次在乌干达从一只哨兵猴身上分离出来。蚊子和哨兵动物监测研究表明，寨卡病毒在非洲和东南亚为地方性流行，但报告的人类病例很少，文献中报道的病例不到10例。2007年6月，在密克罗尼西亚联邦的雅浦州发现了与寨卡病毒相关的发热和皮疹疫情。我们报告了与此次疫情相关的寨卡病毒的基因和血清学特性。