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基于皮肤点刺试验的土耳其婴儿鸡蛋致敏率

Prevalence of egg sensitization in Turkish infants based on skin prick test.

作者信息

Kucukosmanoglu E, Yazi D, Yesil O, Akkoc T, Gezer M, Bakirci N, Bahceciler N N, Barlan I B

机构信息

Gaziantep University Medical Faculty, Department of Pediatrics, Gaziantep, Turkey.

出版信息

Allergol Immunopathol (Madr). 2008 May-Jun;36(3):141-4.

PMID:18680701
Abstract

AIM

Egg allergy is one of the most frequent allergies in infants. The aim of this study was to determine the frequency of sensitization to egg in infants based on skin prick test results and to evaluate associated allergic conditions by questionnaire.

METHODS

All infants born between June 2001 and May 2002 were recalled to the hospital according to their dates of birth, and 1015 infants aged between 8-18 months were included in the study. An interview was conducted with each mother and a questionnaire requesting data on food allergy and other allergic diseases was completed during this interview. An egg skin prick test (whole egg) was applied to all infants.

RESULTS

Positive skin prick test results were recorded in 19 infants (1.87 %). There was no difference between the prick test-positive and -negative groups with respect to any of the demographic characteristics investigated (gender, age, birth weight, egg consumption, age of introduction of egg and other solids, breastfeeding). No significant association was demonstrated between sensitization to egg and family history of allergy. Moreover, there was no association between sensitization to egg and occurrence of atopic dermatitis, recurrent wheezing, gastrointestinal symptoms and doctor diagnosis of asthma.

CONCLUSION

The prevalence of egg sensitization based on skin prick test results has been found as 1.87 % among Turkish infants in Istanbul. However, no significant relationship was found between allergic sensitization to egg and occurrence of allergic diseases in this study population.

摘要

目的

鸡蛋过敏是婴儿中最常见的过敏之一。本研究的目的是根据皮肤点刺试验结果确定婴儿对鸡蛋致敏的频率,并通过问卷调查评估相关的过敏情况。

方法

根据出生日期,将2001年6月至2002年5月出生的所有婴儿召回医院,1015名8至18个月大的婴儿纳入本研究。对每位母亲进行访谈,并在访谈期间完成一份关于食物过敏和其他过敏性疾病数据的问卷。对所有婴儿进行鸡蛋皮肤点刺试验(全蛋)。

结果

19名婴儿(1.87%)的皮肤点刺试验结果呈阳性。在任何调查的人口统计学特征(性别、年龄、出生体重、鸡蛋摄入量、引入鸡蛋和其他固体食物的年龄、母乳喂养)方面,点刺试验阳性组和阴性组之间没有差异。鸡蛋致敏与过敏家族史之间未显示出显著关联。此外,鸡蛋致敏与特应性皮炎、反复喘息、胃肠道症状以及医生诊断的哮喘之间也没有关联。

结论

在伊斯坦布尔的土耳其婴儿中,根据皮肤点刺试验结果发现鸡蛋致敏的患病率为1.87%。然而,在本研究人群中,对鸡蛋的过敏致敏与过敏性疾病的发生之间未发现显著关系。

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