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Nyctohemeral rhythmicity of type II thyroxine 5'-deiodinase activity in the pineal gland but not in the Harderian gland of the Swiss mouse.

作者信息

Rubio A, Osuna C, Lopez-Gonzalez M A, Reiter R J, Guerrero J M

机构信息

University of Seville School of Medicine, Department of Medical Biochemistry and Molecular Biology, Spain.

出版信息

Biosci Rep. 1991 Apr;11(2):111-7. doi: 10.1007/BF01119198.

DOI:10.1007/BF01119198
PMID:1868171
Abstract

Type II thyroxine 5'-deiodinase (5'-D) activity in both pineal and Harderian glands of the Swiss mouse was studied. Pineal 5'-D activity exhibited a nyctohemeral profile with a maximal peak value at 05.00 h, which coincides with that for pineal melatonin production. However, no rhythm of 5'-D activity in the Harderian gland could be found. In pineal gland, light at night inhibited the nocturnal increase in 5'-D activity, while isoproterenol, a beta-adrenergic agonist, could not stimulate the enzyme. In the Harderian gland, neither darkness, nor light or night, or isoproterenol were capable of modifying basal values of 5'-D activity.

摘要

相似文献

1
Nyctohemeral rhythmicity of type II thyroxine 5'-deiodinase activity in the pineal gland but not in the Harderian gland of the Swiss mouse.
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2
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