Murakami M, Greer M A, Greer S E, Hjulstad S, Tanaka K
Department of Medicine, Oregon Health Sciences University, Portland 97201.
Life Sci. 1988;42(19):1875-9. doi: 10.1016/0024-3205(88)90027-6.
Type-II iodothyronine 5'-deiodinase activity (5'-D) in both anterior pituitary and pineal was significantly elevated at 2400 h, approximately 0.5- and 20-fold higher than the noon value, respectively. The nocturnal rise in both organs was abolished by 6 h additional light. Short-term constant darkness did not alter 5'-D rhythmicity in either organ. These data suggest that environmental lighting plays an important role in the control of the 5'-D nyctohemeral rhythm in both anterior pituitary and pineal.
垂体前叶和松果体中的II型甲状腺素5'-脱碘酶活性（5'-D）在24:00时显著升高，分别比中午的值高约0.5倍和20倍。额外6小时光照消除了这两个器官的夜间升高。短期持续黑暗并未改变任一器官中5'-D的节律性。这些数据表明，环境光照在垂体前叶和松果体中5'-D昼夜节律的控制中起着重要作用。
