Jackman H, Radulovacki M
Res Commun Chem Pathol Pharmacol. 1976 Nov;15(3):425-33.
Methysergide maleate, a 5-hydroxytryptamine receptor blocker, was administered to cats deprived of paradoxical sleep for 48 hours. During the first six hours after methysergide, the latency to the first slow-wave sleep and paradoxical sleep episodes was increased and total sleep time decreased. The decrease in sleep reflects a loss of paradoxical sleep, while the amount of slow-wave sleep remained unchanged. Slow-wave sleep time, though unchanged in amount, was displaced to the end of the six-hour recording period. These results suggest that paradoxical sleep in cats is more sensitive to methysergide action than is slow-wave sleep.
将马来酸美西麦角（一种5-羟色胺受体阻滞剂）给予被剥夺异相睡眠48小时的猫。在给予美西麦角后的最初6小时内，首次出现慢波睡眠和异相睡眠发作的潜伏期延长，总睡眠时间减少。睡眠减少反映了异相睡眠的丧失，而慢波睡眠量保持不变。慢波睡眠时间虽然总量不变，但被推迟到6小时记录期的末尾。这些结果表明，猫的异相睡眠比慢波睡眠对美西麦角的作用更敏感。
