甲磺酸双氢麦角毒碱（Redergine）对剥夺异相睡眠的猫睡眠的影响。

Effects of dihydroergotoxine methane sulphonate (Redergine) on sleep in cats deprived of paradoxical sleep.

作者信息

Susić V, Ponomarev D, Bosković J, Masirević G

出版信息

Arch Int Physiol Biochim. 1981 Dec;89(5):411-5.

Abstract

Dihydroergotoxine methane sulphonate (DHET 1.0 mg/kg i.p.) was administered to cats deprived of paradoxical sleep (PS) for 72 h and 23 h of recovery sleep were recorded. During the first 12 h of recovery sleep slow-wave sleep (SWS) was significantly increased. There were no significant changes in the amounts of wakefulness (W), PS and several sleep indices. Analysis of the entire 23 h of recording period revealed no significant changes in any of the parameters studied. The results suggest that DHET has SWS enhancing property in the condition where "pressure" for PS was increased.

摘要

将甲磺酸双氢麦角毒碱（DHET，腹腔注射，剂量为1.0毫克/千克）给予剥夺异相睡眠（PS）72小时的猫，并记录23小时的恢复睡眠情况。在恢复睡眠的前12小时，慢波睡眠（SWS）显著增加。觉醒量（W）、PS及几个睡眠指标均无显著变化。对整个23小时记录期的分析表明，所研究的任何参数均无显著变化。结果表明，在PS“压力”增加的情况下，DHET具有增强SWS的特性。