Susić V, Kovacević R, Momirov D, Masirević G
Arch Int Physiol Biochim. 1977 Aug;85(3):455-9.
This study examined the effects of clozapine on sleep-wakefulness profile in cats prepared for chronic recording of sleep. Clozapine in single dose (i.p.) of 5 mg/kg drastically reduced slow-wave sleep (SWS) and paradoxical sleep (PS), while wakefulness and drowsy pattern were increased. These changes lasted approximately 24 h and were followed by sleep recovery. PS had a priority of recovery. Some similarities between clozapine effects on sleep in cat and human were mentioned.
本研究考察了氯氮平对为长期记录睡眠而准备的猫的睡眠-觉醒状态的影响。腹腔注射5毫克/千克单剂量的氯氮平可显著减少慢波睡眠（SWS）和异相睡眠（PS），同时增加觉醒和困倦状态。这些变化持续约24小时，随后睡眠恢复。异相睡眠优先恢复。文中提到了氯氮平对猫和人类睡眠影响的一些相似之处。
