• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Protease-triggered unveiling of bioactive nanoparticles.蛋白酶触发的生物活性纳米颗粒的暴露
Small. 2008 Sep;4(9):1307-12. doi: 10.1002/smll.200701319.
2
Tumor-targeting and microenvironment-responsive smart nanoparticles for combination therapy of antiangiogenesis and apoptosis.肿瘤靶向和微环境响应智能纳米颗粒用于抗血管生成和细胞凋亡联合治疗。
ACS Nano. 2013 Mar 26;7(3):2860-71. doi: 10.1021/nn400548g. Epub 2013 Mar 12.
3
Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo.用于体外和体内靶向肿瘤治疗的酶响应性介孔二氧化硅纳米颗粒。
Nanoscale. 2015 Feb 28;7(8):3614-26. doi: 10.1039/c5nr00072f.
4
Particle replication in nonwetting templates nanoparticles with tumor selective alkyl silyl ether docetaxel prodrug reduces toxicity.在具有肿瘤选择性烷基硅烷基醚多西他赛前药的非润湿模板纳米颗粒中的颗粒复制可降低毒性。
Nano Lett. 2014 Mar 12;14(3):1472-6. doi: 10.1021/nl4046558. Epub 2014 Feb 24.
5
Preparation of neutron-activatable holmium nanoparticles for the treatment of ovarian cancer metastases.用于治疗卵巢癌转移的可激活中子铥纳米颗粒的制备。
Small. 2012 Apr 10;8(7):997-1000. doi: 10.1002/smll.201102488. Epub 2012 Feb 2.
6
Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging.通过多模态成像研究表面转换纳米颗粒在肿瘤中的细胞特异性。
Bioconjug Chem. 2017 May 17;28(5):1413-1421. doi: 10.1021/acs.bioconjchem.7b00086. Epub 2017 May 5.
7
Enzyme-responsive multistage vector for drug delivery to tumor tissue.用于将药物递送至肿瘤组织的酶响应性多级载体。
Pharmacol Res. 2016 Nov;113(Pt A):92-99. doi: 10.1016/j.phrs.2016.08.024. Epub 2016 Aug 19.
8
Tumor-targeting gold particles for dual computed tomography/optical cancer imaging.用于双模态计算机断层扫描/光学癌症成像的肿瘤靶向金纳米颗粒
Angew Chem Int Ed Engl. 2011 Sep 26;50(40):9348-51. doi: 10.1002/anie.201102892. Epub 2011 Aug 26.
9
Enzyme-Activatable Interferon-Poly(α-amino acid) Conjugates for Tumor Microenvironment Potentiation.酶激活型干扰素聚（α-氨基酸）缀合物用于增强肿瘤微环境。
Biomacromolecules. 2019 Aug 12;20(8):3000-3008. doi: 10.1021/acs.biomac.9b00560. Epub 2019 Jul 31.
10
A self-assembled pH/enzyme dual-responsive prodrug with PEG deshielding for multidrug-resistant tumor therapy.具有 PEG 去屏蔽的自组装 pH/酶双重响应前药用于多药耐药肿瘤治疗。
J Mater Chem B. 2020 Feb 14;8(6):1290-1301. doi: 10.1039/c9tb02264c. Epub 2020 Jan 22.

引用本文的文献

1
Quenching of nonlinear photoacoustic signal generation in gold nanoparticles through coating.通过包覆抑制金纳米颗粒中非线性光声信号的产生。
Nanoscale Adv. 2020 Jun 18;2(7):2699-2704. doi: 10.1039/d0na00205d. eCollection 2020 Jul 14.
2
Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate-Caged Guanidine Lipid.硼笼胍脂质激活的活性氧物种（ROS）脂质体细胞递送。
Chemistry. 2022 Aug 16;28(46):e202201057. doi: 10.1002/chem.202201057. Epub 2022 Jun 27.
3
Multifunctional and stimuli-responsive nanocarriers for targeted therapeutic delivery.多功能和刺激响应型纳米载体用于靶向治疗递送。
Expert Opin Drug Deliv. 2021 Feb;18(2):205-227. doi: 10.1080/17425247.2021.1828339. Epub 2020 Oct 8.
4
Stimuli-Responsive Biomaterials for Vaccines and Immunotherapeutic Applications.用于疫苗和免疫治疗应用的刺激响应性生物材料。
Adv Ther (Weinh). 2020 Nov;3(11):2000129. doi: 10.1002/adtp.202000129. Epub 2020 Aug 2.
5
Developing Nanoceria-Based pH-Dependent Cancer-Directed Drug Delivery System for Retinoblastoma.开发用于视网膜母细胞瘤的基于纳米氧化铈的pH依赖性癌症导向药物递送系统。
Adv Funct Mater. 2018 Dec 27;28(52). doi: 10.1002/adfm.201806248. Epub 2018 Nov 12.
6
Activity-Based Diagnostics: An Emerging Paradigm for Disease Detection and Monitoring.基于活性的诊断：一种用于疾病检测和监测的新兴范式。
Trends Mol Med. 2020 May;26(5):450-468. doi: 10.1016/j.molmed.2020.01.013. Epub 2020 Apr 5.
7
Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging.靶向磁共振成像对比剂的基因编码用于肿瘤成像。
ACS Synth Biol. 2020 Feb 21;9(2):392-401. doi: 10.1021/acssynbio.9b00416. Epub 2020 Jan 22.
8
Clinical Cancer Nanomedicine.临床癌症纳米医学
Nano Today. 2019 Apr;25:85-98. doi: 10.1016/j.nantod.2019.02.005. Epub 2019 Mar 6.
9
Activated Charge-Reversal Polymeric Nano-System: The Promising Strategy in Drug Delivery for Cancer Therapy.活化电荷反转聚合物纳米系统：癌症治疗药物递送中的前景策略。
Polymers (Basel). 2016 Apr 5;8(4):99. doi: 10.3390/polym8040099.
10
Cell penetrating peptides in preclinical and clinical cancer diagnosis and therapy.细胞穿透肽在临床前和临床癌症诊断与治疗中的应用
Oncotarget. 2018 Dec 14;9(98):37252-37267. doi: 10.18632/oncotarget.26442.

本文引用的文献

1
"Smart" drug carriers: PEGylated TATp-modified pH-sensitive liposomes.“智能”药物载体：聚乙二醇化TATp修饰的pH敏感脂质体
J Liposome Res. 2007;17(3-4):197-203. doi: 10.1080/08982100701525035.
2
Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging.通过多模态体内成像测量肿瘤特异性靶向对siRNA纳米颗粒生物分布和疗效的影响。
Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15549-54. doi: 10.1073/pnas.0707461104. Epub 2007 Sep 17.
3
Nanoparticle self-assembly gated by logical proteolytic triggers.由逻辑蛋白水解触发因素控制的纳米颗粒自组装
J Am Chem Soc. 2007 May 16;129(19):6064-5. doi: 10.1021/ja070461l. Epub 2007 Apr 21.
4
Multifunctional nanocarriers.多功能纳米载体。
Adv Drug Deliv Rev. 2006 Dec 1;58(14):1532-55. doi: 10.1016/j.addr.2006.09.009. Epub 2006 Sep 28.
5
Protease-modulated cellular uptake of quantum dots.蛋白酶调节的量子点细胞摄取
Nano Lett. 2006 Sep;6(9):1988-92. doi: 10.1021/nl0611586.
6
Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid.利用肿瘤特异性可裂解聚乙二醇脂质开发用于癌症治疗的新型全身基因递送系统。
Gene Ther. 2007 Jan;14(1):68-77. doi: 10.1038/sj.gt.3302843. Epub 2006 Aug 17.
7
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models.在动物模型中，对长循环脂质纳米颗粒进行抗体靶向不会增加肿瘤定位，但会增加内化。
Cancer Res. 2006 Jul 1;66(13):6732-40. doi: 10.1158/0008-5472.CAN-05-4199.
8
Proteolytic actuation of nanoparticle self-assembly.纳米颗粒自组装的蛋白水解驱动
Angew Chem Int Ed Engl. 2006 May 5;45(19):3161-5. doi: 10.1002/anie.200600259.
9
Super pH-sensitive multifunctional polymeric micelle.超pH敏感多功能聚合物胶束。
Nano Lett. 2005 Feb;5(2):325-9. doi: 10.1021/nl0479987.
10
Tumor imaging by means of proteolytic activation of cell-penetrating peptides.通过细胞穿透肽的蛋白水解激活进行肿瘤成像。
Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17867-72. doi: 10.1073/pnas.0408191101. Epub 2004 Dec 15.

Protease-triggered unveiling of bioactive nanoparticles.

作者信息

Harris Todd J, von Maltzahn Geoffrey, Lord Matthew E, Park Ji-Ho, Agrawal Amit, Min Dal-Hee, Sailor Michael J, Bhatia Sangeeta N

机构信息

Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology E19-502D Cambridge, MA 02139, USA.

出版信息

Small. 2008 Sep;4(9):1307-12. doi: 10.1002/smll.200701319.

DOI:10.1002/smll.200701319
PMID:18690639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2759667/
Abstract
摘要