Ahmed Ayesha, Alam Mian Bilal, Khan Waheed, Badar Ahmed, Shah Syed Humayun
Department of Pathology, Ayub Medical College, Abbottabad, Pakistan.
J Ayub Med Coll Abbottabad. 2007 Oct-Dec;19(4):3-6.
Our histopathology laboratory serves mountainous area of Hazara Division in Northern Pakistan. This study is an analysis of the records of skin cancers reported over a nine years period to develop local statistics about frequency and characteristics of skin cancers.
Data from 1995-2003 record of cancers reported by Department of Pathology, Ayub Medical College, Abbottabad were analysed to calculate cumulative and year wise frequency of skin cancers and their major types. Frequency distribution with reference to gender and age was also calculated.
Skin cancers were 220 (1.04%) out of the total 21075 cancers recorded during this period. Squamous cell carcinoma was diagnosed in 118 (53.6%), Basal cell carcinoma in 88 (40%) and Malignant melanoma in 14 (6.4%) cases. The mean age for all skin cancers considered together was 58.75 +/- 15.21. Non Melanoma Skin Cancer (NMSC) were seen in all age groups (minimum 15, maximum 103 years), while no malignant melanoma patient was under 35 years of age. Gender difference in distribution was negligible with slight male preponderance (23:21). Malignant melanoma was significantly (p < 0.05) more in males (71.4%), while distribution of both the types of NMSC was non-significantly in favour of males. We found no significant rise or fall in total skin cancers or any type of skin cancer in this 9 years period.
At present the frequency of skin cancer is stable at around 1% of total cancers reported at Ayub Medical College, reflecting a stable very low incidence rate of skin cancer in Hazara Division of Pakistan.
我们的组织病理学实验室服务于巴基斯坦北部哈扎拉地区的山区。本研究分析了九年间报告的皮肤癌记录，以得出有关皮肤癌发病率和特征的当地统计数据。
对阿伯塔巴德阿尤布医学院病理科1995 - 2003年报告的癌症记录数据进行分析，计算皮肤癌及其主要类型的累积发病率和逐年发病率。还计算了性别和年龄的频率分布。
在此期间记录的21075例癌症中，皮肤癌有220例（1.04%）。鳞状细胞癌诊断出118例（53.6%），基底细胞癌88例（40%），恶性黑色素瘤14例（6.4%）。所有皮肤癌患者的平均年龄为58.75±15.21岁。非黑色素瘤皮肤癌（NMSC）在所有年龄组均有发现（最小15岁，最大103岁），而恶性黑色素瘤患者年龄均在35岁以上。性别分布差异可忽略不计，男性略占优势（23:21）。男性恶性黑色素瘤显著更多（p < 0.05）（71.4%），而两种类型的NMSC在男性中的分布无显著差异。我们发现在这9年期间，皮肤癌总数或任何类型的皮肤癌均无显著上升或下降。
目前，阿尤布医学院报告的皮肤癌发病率稳定在约1%，反映出巴基斯坦哈扎拉地区皮肤癌发病率非常低且稳定。
