Wahid Abdul, Ahmad Sajjad, Sajjad Mohammad
Department of Dentistry and Pathology, Ayub Medical College, Abbottabad.
J Ayub Med Coll Abbottabad. 2005 Jan-Mar;17(1):65-6.
Carcinoma of oral cavity is amongst the first ten commonest malignancies in Pakistan. Districts of Hazara (NWFP) and Northern Areas of Pakistan are among the high risk. areas. Here we present a report of oral cancers received in this center over a period of 10 years. METHODDS: This clinicopathological study consists of cases of carcinoma of oral cavity presenting to dentistry department of Ayub Medical College Abbottabad during 1993-2003. All cases were clinically examined and provisionally diagnosed. Biopsy was taken from all the lesions and the tissues submitted to histopathology department of Ayub Medical College.
There were 50 carcinoma cases in the study, including 30 (60%) males and 20 (40%) females. Among these, 47 (94%,) were diagnosed as squamous cell carcinomas, that consisted 30 (63.82 %) males and 17 (36.17%) females. The other 6 % lesions were histologically diagnosed as malignant melanoma, adenocarcinoma and acinar cell carcinoma. The age of squamous cell carcinoma cases was 41-71 years. The maximum number of squamous cell carcinomas (34%) effected buccal mucosa. The other common sites were lip (26%), tongue (21%) and gums (19%).
The results of this study are comparable with other such studies done in Pakistan and else where in the world showing commonality of factors associated with the development of the disease in this region of the country, which necessitates a detailed prospective study.
口腔癌是巴基斯坦最常见的十大恶性肿瘤之一。哈扎拉地区（西北边境省）和巴基斯坦北部地区属于高风险地区。在此，我们报告本中心10年间收治的口腔癌病例。
本临床病理研究包括1993年至2003年期间在阿伯塔巴德阿尤布医学院牙科就诊的口腔癌病例。所有病例均经过临床检查并初步诊断。对所有病变进行活检，并将组织送检至阿尤布医学院组织病理学科室。
本研究中有50例癌症病例，其中男性30例（60%），女性20例（40%）。其中，47例（94%）被诊断为鳞状细胞癌，包括男性30例（63.82%），女性17例（36.17%）。另外6%的病变经组织学诊断为恶性黑色素瘤、腺癌和腺泡细胞癌。鳞状细胞癌病例的年龄在41至71岁之间。鳞状细胞癌最多见的部位是颊黏膜（34%）。其他常见部位是唇（26%）、舌（21%）和牙龈（19%）。
本研究结果与在巴基斯坦及世界其他地方进行的其他此类研究结果相当，表明该国该地区与该疾病发生相关的因素具有共性，这需要进行详细的前瞻性研究。
