成年马免疫球蛋白同种型的正态分布。

Normal distribution of immunoglobulin isotypes in adult horses.

作者信息

de Camargo Maristela M, Kuribayashi Juliana S, Bombardieri Cíntia R, Hoge Alma

机构信息

Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1730, São Paulo, SP 05508-900, Brazil.

出版信息

Vet J. 2009 Nov;182(2):359-61. doi: 10.1016/j.tvjl.2008.05.014. Epub 2008 Aug 9.

DOI:10.1016/j.tvjl.2008.05.014

PMID:18694652

Abstract

Studies focusing on the equine humoral response are scarce, with a bias towards the pre- and post-parturition mare and its foal. The present study attempted to expand current knowledge by establishing normal ranges for adult horse serum isotypes. Immunoglobulin (Ig) concentrations were obtained by screening 47 horses of various breeds and in different training regimes. Radial immunodiffusion values (mg/dL) were 196+/-73 for IgA, 2704+/-1424 for IgG, 419+/-220 for IgG(T) and 70+/-30 for IgM. All values passed the Kolmogorov-Smirnov normality test. The results will be of use to the field veterinarian as well for the basic researcher working on horses.

摘要

关于马的体液反应的研究很少，且偏向于产前和产后母马及其幼驹。本研究试图通过建立成年马血清同种型的正常范围来扩展当前的知识。通过对47匹不同品种和处于不同训练状态的马进行筛查，获得了免疫球蛋白（Ig）浓度。IgA的单向免疫扩散值（mg/dL）为196±73，IgG为2704±1424，IgG(T)为419±220，IgM为70±30。所有值均通过了柯尔莫哥洛夫-斯米尔诺夫正态性检验。这些结果将对野外兽医以及从事马研究的基础研究人员有用。