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健康日本中年男性的衰老男性症状与血清睾酮水平

[Aging male symptoms and serum testosterone levels in healthy Japanese middle-aged men].

作者信息

Kawa Gen, Taniguchi Hisanori, Kinoshita Hidefumi, Matsuda Tadashi, Urakami Masaya, Sawaragi Isamu

机构信息

Department of Urology and Andrology, Kansai Medical University.

出版信息

Nihon Hinyokika Gakkai Zasshi. 2008 Jul;99(5):645-51. doi: 10.5980/jpnjurol1989.99.645.

DOI:10.5980/jpnjurol1989.99.645
PMID:18697471
Abstract

OBJECTIVE

To evaluate the usefulness of the ADAM questionnaire and aging males' symptoms' (AMS) rating scale for Japanese middle-aged men, we analyzed the results of these tests. We also examined the range of serum testosterone levels of these individuals.

MATERIAL & METHODS: Answers to these tests were obtained from 187 healthy Japanese men (from 46 to 64 years old) who visited for medical check-up. Serum total (TT) and free (FT) testosterone were also examined, and calculated free (cFT) and bioavalable (cBT) testosterone levels were obtained.

RESULT

According to the ADAM questionnaire, 140 (77.8%) men were judged to be PADAM. Mean AMS total, psychological, somatovegetative, and sexual symptom scores were 29.4, 7.5, 12.9, and 9.0, respectively. Although 32 (17.5%) men had more than moderate symptoms on AMS total score, 119 (65.0%) men complained of more than moderate sexual symptoms. In contrast, the testosterone levels of these people were not always low. Mean values of TT, FT, cFT, and cBT were 5.50 ng/ml, 14.7 pg/ml, 116.1 pg/ml, and 292.3 ng/dl, respectively. None of these testosterone levels was significantly correlated with age or AMS score. Only sexual symptom score among AMS subscales was significantly correlated with age.

CONCLUSION

The borderlines for the ADAM questionnaire and AMS rating scale appear too stringent for healthy Japanese middle-aged men. The sexual activity of Japanese middle-aged men appears less than that of Westerners. Criteria of these tests in Japanese middle-aged men, especially sexual function, should be changed.

摘要

目的

为评估ADAM问卷和老年男性症状(AMS)评分量表对日本中年男性的实用性,我们分析了这些测试的结果。我们还检测了这些个体的血清睾酮水平范围。

材料与方法

对187名前来体检的健康日本男性(46至64岁)进行了这些测试的问卷调查。同时检测了血清总睾酮(TT)和游离睾酮(FT),并计算出游离睾酮(cFT)和生物可利用睾酮(cBT)水平。

结果

根据ADAM问卷,140名(77.8%)男性被判定为部分雄激素缺乏性性腺功能减退症(PADAM)。AMS总分、心理症状、躯体植物神经症状和性症状的平均得分分别为29.4、7.5、12.9和9.0。虽然32名(17.5%)男性的AMS总分有中度以上症状,但119名(65.0%)男性抱怨有中度以上的性症状。相比之下,这些人的睾酮水平并非总是很低。TT、FT、cFT和cBT的平均值分别为5.50 ng/ml、14.7 pg/ml、116.1 pg/ml和292.3 ng/dl。这些睾酮水平均与年龄或AMS评分无显著相关性。AMS各子量表中只有性症状评分与年龄显著相关。

结论

对于健康的日本中年男性,ADAM问卷和AMS评分量表的临界值似乎过于严格。日本中年男性的性活动似乎低于西方人。这些测试在日本中年男性中的标准,尤其是性功能方面的标准,应该改变。

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