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[Two cases of radiation-induced sarcoma after radiation therapy in nasopharyngeal carcinoma].

作者信息

Okoshi Akira, Shiga Kiyoto, Sasaki Kazuha, Asada Yukinori, Nishikawa Hitoshi, Kobayashi Toshimitsu, Watanabe Mika

机构信息

Department of Otolaryngology-Head & Neck Surgery, Tohoku University Hospital, Sendai.

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 2008 Jul;111(7):533-6. doi: 10.3950/jibiinkoka.111.533.

Abstract

We report two cases of radiation-induced sarcoma after chemoradiation therapy in nasopharyngeal carcinoma. Case 1: A 40-year-old man developed a malignant peripheral nerve sheath tumor (MPNST) in the posterior floor of the nasal cavity 10 years after treatment for nasopharyngeal cancer. Case 2: A 64 year-old man developed a malignant fibrous histiocytoma (MFH) of the lower gum 10 years after treatment of nasopharyngeal cancer. Despite radical surgery, the man with MPNST had a recurrent tumor and died of the disease.

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