Okoshi Akira, Shiga Kiyoto, Sasaki Kazuha, Asada Yukinori, Nishikawa Hitoshi, Kobayashi Toshimitsu, Watanabe Mika
Department of Otolaryngology-Head & Neck Surgery, Tohoku University Hospital, Sendai.
Nihon Jibiinkoka Gakkai Kaiho. 2008 Jul;111(7):533-6. doi: 10.3950/jibiinkoka.111.533.
We report two cases of radiation-induced sarcoma after chemoradiation therapy in nasopharyngeal carcinoma. Case 1: A 40-year-old man developed a malignant peripheral nerve sheath tumor (MPNST) in the posterior floor of the nasal cavity 10 years after treatment for nasopharyngeal cancer. Case 2: A 64 year-old man developed a malignant fibrous histiocytoma (MFH) of the lower gum 10 years after treatment of nasopharyngeal cancer. Despite radical surgery, the man with MPNST had a recurrent tumor and died of the disease.
我们报告了两例鼻咽癌放化疗后发生放射性肉瘤的病例。病例1：一名40岁男性在鼻咽癌治疗10年后，鼻腔后底部发生了恶性外周神经鞘瘤（MPNST）。病例2：一名64岁男性在鼻咽癌治疗10年后，下牙龈发生了恶性纤维组织细胞瘤（MFH）。尽管接受了根治性手术，但患有MPNST的男性出现了肿瘤复发并死于该疾病。
