Vignon F, Vivier C, Roll-Back M H, Clavert A, Cranz C, Reville P
Laboratoire d'Endocrinologie expérimentale, CHRU, Hôpital Central, Strasbourg.
J Gynecol Obstet Biol Reprod (Paris). 1991;20(3):321-4.
The aim of this work is to study and compare lipid composition of peritoneal and ovulatory follicular fluid of women. The studied patients are involved in a FIV protocol. We have studied 53 peritoneal fluids and 90 follicular fluids from 33 patients. On each sample the following parameters are estimated: cholesterol, triglycerides, phospholipids, non esterified fatty acids (A.G.N.E.), HDL and LDL cholesterol, HDL and LDL phospholipids. Lipid composition of follicular and peritoneal fluids differ from these of blood plasma. The two mediums studies show no differences with regard to their lipid composition. In both cholesterol is only found as HDL cholesterol. Cholesterol arising from spermatozoa membranes may be implicated in capacitation phenomenon. HDL Cholesterol, the only form found in the studied mediums, may act as a cholesterol acceptor. Theses two points partially explain the fact that follicular and peritoneal fluids are good mediums for capacitation and survival of spermatozoa.
这项工作的目的是研究和比较女性腹膜液和排卵卵泡液的脂质组成。所研究的患者参与了体外受精方案。我们研究了来自33名患者的53份腹膜液和90份卵泡液。对每个样本估计以下参数：胆固醇、甘油三酯、磷脂、非酯化脂肪酸（AGNE）、高密度脂蛋白和低密度脂蛋白胆固醇、高密度脂蛋白和低密度脂蛋白磷脂。卵泡液和腹膜液的脂质组成与血浆不同。所研究的两种介质在脂质组成方面没有差异。在这两种介质中，胆固醇仅以高密度脂蛋白胆固醇的形式存在。精子细胞膜产生的胆固醇可能与获能现象有关。高密度脂蛋白胆固醇是在所研究介质中发现的唯一形式，可能作为胆固醇受体。这两点部分解释了卵泡液和腹膜液是精子获能和存活的良好介质这一事实。
