Menezo Y, Testart J, Khatchadourian C, Frydman R
Int J Fertil. 1984;29(2):61-4.
The lipid content of human follicles within 6 h of ovulation was determined. Levels for triglycerides, phospholipids, and total cholesterol were 1/4 to 1/3 of those in serum. An uncommonly high level of free cholesterol was observed, possibly resulting from a high synthetic rate by the granulosa. Follicular lipids appear to be of serum origin since the relative proportions of the various fatty acids are the same. Arachidonic acid was not found to be present at the high levels reported for "large" porcine follicles, possibly due to its active utilization in the synthesis of prostaglandins necessary for the ovulation process. Precise timing relative to ovulation is clearly essential for follicular classification in order to distinguish between before and after the triggering of the ovulation process. A possible role for lipids in the induction of capacitation is proposed.
测定了排卵后6小时内人卵泡的脂质含量。甘油三酯、磷脂和总胆固醇水平为血清中相应水平的1/4至1/3。观察到游离胆固醇水平异常高，这可能是由于颗粒细胞合成率高所致。卵泡脂质似乎来源于血清，因为各种脂肪酸的相对比例相同。未发现花生四烯酸以报道的“大型”猪卵泡中的高水平存在，这可能是由于其在排卵过程所需的前列腺素合成中被积极利用。为了区分排卵过程触发之前和之后的卵泡，相对于排卵的精确时间对于卵泡分类显然至关重要。提出了脂质在诱导获能中的可能作用。
