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斯洛伐克人乳中赭曲霉毒素A出现情况的首批研究结果。

Results of the first studies of occurence of ochratoxin A in human milk in Slovakia.

作者信息

Dostal A, Jakusova L, Cajdova J, Hudeckova H

机构信息

Institute of Public Health, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia.

出版信息

Bratisl Lek Listy. 2008;109(6):276-8.

Abstract

UNLABELLED

Authors bring the work the purpose of which is to offer information about quality of human milk from the viewpoint of possible contamination with mycotoxin Ochratoxin A from the fist analyses in Slovakia. One of its main toxic effect is nephrotoxicity, immunotoxicity, neurotoxicity, teratogenity and carcinogenity.

MATERIAL AND PROCEDURE

76 samples of human milk from locality Martin and the corresponding zone were analysed by technique of High Performance Liquid Chromatography (HPLC) in conditions as mentioned below.

RESULTS

Ochratoxin A was proved in 23 samples, 9 samples of the number with values from 2.3 +/- 0.99 ng/l to 60.3 +/- 25.93 ng/l, its occurence was at the level of quantification limit in the other 14 samples and it was undetectable in 55 samples of human milk.

CONCLUSION

Up to now findings of our study have pointed out that Ochratoxin A can occur in human milk also in our conditions and determined values range between limits like those in Germany and Switzerland (Tab. 3, Fig. 1, Ref. 15).

摘要

未标注

作者开展此项工作的目的是,从斯洛伐克首次分析的角度,提供有关人乳中可能被赭曲霉毒素A污染情况的质量信息。其主要毒性作用之一是肾毒性、免疫毒性、神经毒性、致畸性和致癌性。

材料与方法

采用高效液相色谱法(HPLC),在如下所述条件下,对来自马丁地区及相应区域的76份人乳样本进行了分析。

结果

在23份样本中检测到赭曲霉毒素A,其中9份样本的值为2.3±0.99纳克/升至60.3±25.93纳克/升,另外14份样本中其含量处于定量限水平,55份人乳样本中未检测到该毒素。

结论

目前我们的研究结果指出,在我们的环境条件下,人乳中也可能存在赭曲霉毒素A,其测定值范围与德国和瑞士的限值相当(表3,图1,参考文献15)。

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