Wainwright N W J, Surtees P G, Welch A A, Luben R N, Khaw K-T, Bingham S A
Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.
J Epidemiol Community Health. 2008 Sep;62(9):829-31. doi: 10.1136/jech.2007.066464.
Based on data from the European Prospective Investigation into Cancer, Norfolk (EPIC-Norfolk) study, we have previously shown a strong sense of coherence (SOC) to be associated with a reduced rate of all-cause mortality.
To investigate the extent to which the SOC mortality association can be explained by socioeconomic status and lifestyle choices.
Prospective population-based cohort study.
18 287 study participants aged 41-80 years who reported no pre-existing chronic disease at baseline and who completed an assessment of SOC.
Based on 1599 deaths during a mean follow-up of 8.3 years, a strong SOC was associated with a 20% reduced risk of all-cause mortality. Measures of lifestyle choice (cigarette smoking, physical activity, dietary intakes of fruit, vegetables and fibre) and socioeconomic status (social class and education) explained 23% of this association.
The SOC concept embraces multiple sets of chronic disease risk factors that include lifestyle choices and those associated with socioeconomic status, and is a potential aid in understanding differences in health outcomes in similar individuals.
基于欧洲癌症前瞻性调查诺福克（EPIC - 诺福克）研究的数据，我们之前已表明，较强的连贯感（SOC）与全因死亡率降低相关。
调查社会经济地位和生活方式选择在多大程度上能够解释SOC与死亡率之间的关联。
基于人群的前瞻性队列研究。
18287名年龄在41 - 80岁之间的研究参与者，他们在基线时报告无既往慢性病且完成了SOC评估。
在平均8.3年的随访期间有1599例死亡，较强的SOC与全因死亡率风险降低20%相关。生活方式选择（吸烟、体育活动、水果、蔬菜和纤维的饮食摄入量）和社会经济地位（社会阶层和教育程度）指标解释了这种关联的23%。
SOC概念包含多组慢性病风险因素，其中包括生活方式选择以及与社会经济地位相关的因素，并且在理解相似个体健康结果差异方面可能有所帮助。
