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西班牙造纸、纸浆和纸板行业附近城镇的肺癌死亡率:一项点源污染研究。

Lung cancer mortality in towns near paper, pulp and board industries in Spain: a point source pollution study.

作者信息

Monge-Corella Susana, García-Pérez Javier, Aragonés Nuria, Pollán Marina, Pérez-Gómez Beatriz, López-Abente Gonzalo

机构信息

Cancer and Environmental Epidemiology Area, National Centre for Epidemiology, Carlos III Institute of Health, Madrid, Spain.

出版信息

BMC Public Health. 2008 Aug 14;8:288. doi: 10.1186/1471-2458-8-288.

Abstract

BACKGROUND

This study sought to ascertain whether there might be excess lung cancer mortality among the population residing in the vicinity of Spanish paper and board industries which report their emissions to the European Pollutant Emission Register (EPER).

METHODS

This was an ecological study that modelled the Standardised Mortality Ratio (SMR) for lung cancer in 8073 Spanish towns over the period 1994-2003. Population exposure to industrial pollution was estimated on the basis of distance from town of residence to pollution source. An exploratory, near-versus-far analysis was conducted, using mixed Poisson regression models and an analysis of the effect of municipal proximity within a 50-kilometre radius of each of the 18 installations.

RESULTS

Results varied for the different facilities. In two instances there was an increasing mortality gradient with proximity to the installation, though this was exclusively observed among men.

CONCLUSION

The study of cancer mortality in areas surrounding pollutant foci is a useful tool for environmental surveillance, and serves to highlight areas of interest susceptible to being investigated by ad hoc studies. Despite present limitations, recognition is therefore due to the advance represented by publication of the EPER and the study of pollutant foci.

摘要

背景

本研究旨在确定居住在向欧洲污染物排放登记册(EPER)报告其排放情况的西班牙造纸及纸板行业附近的人群中,肺癌死亡率是否可能过高。

方法

这是一项生态研究,对1994 - 2003年期间西班牙8073个城镇的肺癌标准化死亡率(SMR)进行建模。根据居民所在城镇与污染源的距离估算人群对工业污染的暴露程度。使用混合泊松回归模型进行探索性的近距与远距分析,并分析了18个设施中每个设施半径50公里范围内城市接近程度的影响。

结果

不同设施的结果各不相同。在两个案例中,随着与设施距离的接近,死亡率呈上升梯度,但这仅在男性中观察到。

结论

对污染物聚集区周围癌症死亡率的研究是环境监测的有用工具,有助于突出那些适合通过专项研究进行调查的感兴趣区域。尽管存在当前的局限性,但EPER的发布以及对污染物聚集区的研究代表的进步值得认可。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca2/2527328/a837ad4b5c74/1471-2458-8-288-1.jpg

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