Kent P, Wilkinson D, Parkin A, Kester R C
Vascular Laboratory, St. James's University Hospital, Leeds, UK.
J Biomed Eng. 1991 May;13(3):260-2. doi: 10.1016/0141-5425(91)90138-w.
The present staging of the disease severity of vibration induced white finger (VWF) is based on the patients' symptoms. Forty patients, with a history of VWF, with disease severity stage III or stage IV, on the Taylor-Pelmear scale, were investigated. Total, reactive hyperaemic blood flow to the hands was measured using an isotope limb blood flow (ILBF) technique. Skin blood flow patterns were assessed using a cold provocation test, followed by thermographic assessment of hand rewarming. Thermographic abnormalities were detected in 39 patients (97%). Decreased post-occlusive, reactive hyperaemic blood flow occurred in 29 patients (73%). There was no difference in skin blood flow patterns or in total hand blood flow between the stage III and stage IV groups. Reduction of postocclusive reactive hyperaemic blood flow may be indicative of occlusive lesions of the digital vessels. We conclude that the classification of the severity of VWF using subjective assessment, needs to be augmented by objective evidence of altered blood flow.
目前振动性白指（VWF）疾病严重程度的分期是基于患者的症状。对40名有VWF病史、按照泰勒 - 佩尔米尔量表疾病严重程度为III期或IV期的患者进行了调查。使用同位素肢体血流（ILBF）技术测量手部总的反应性充血血流量。采用冷激发试验评估皮肤血流模式，随后对手部复温进行热成像评估。39名患者（97%）检测到热成像异常。29名患者（73%）出现闭塞后反应性充血血流量减少。III期和IV期组之间在皮肤血流模式或手部总血流量方面没有差异。闭塞后反应性充血血流量的减少可能表明手指血管存在闭塞性病变。我们得出结论，使用主观评估对VWF严重程度进行分类，需要通过血流改变的客观证据加以补充。
