von Bierbrauer A, Schilk I, Lucke C, Schmidt J A
Department of Internal Medicine, Medical Policlinic-Angiology, Philipps University, Marburg, Germany.
Vasa. 1998 May;27(2):94-9.
Frequent use of vibrating tools over several years may lead to a neurovascular disturbance of finger circulation with the development of typical Raynaud's phenomenon, attacks being triggered by vibration and/or cold exposure. The condition is recognized as an occupational disease and known as vibration-induced white finger (VWF). Aim of the present study was to evaluate the usefulness of infrared thermography (IRT) with a cold provocation test in the diagnosis of Raynaud's phenomenon in VWF.
24 patients with the diagnosis of VWF, previously established by other methods, were compared with 12 matched control subjects. We carried out IRT-measurements simultaneously on both hands before, directly after and 5, 10, 15, 20, and 30 mins following a 3 min exposure of both hands to a waterbath of 12 degrees C. The results of temperature measurements of all fingers were analyzed and the time to complete rewarming of all fingers was recorded.
The basal thermograms did not differ between both groups, whereas the mean finger temperatures after cold exposure were significantly lower in VWF-patients compared to controls, with a considerable individual overlap between both groups. Therefore, determination of absolute finger temperature reveals not to be a useful diagnostic tool in individual cases, but might be helpful for pharmacological studies (group-analysis). In contrast to absolute finger temperatures, the parameter of rewarming time after cold exposure revealed to be diagnostic on an individual basis: a complete rewarming after 15 min indicates a normal vascular reactivity and an incomplete rewarming 30 min following the cold provocation points to an impaired vascular reactivity due to VWF.
IRT revealed to be a useful tool in the diagnosis of Raynaud's phenomenon in VWF, and provides a sufficient documentation suitable for further follow-up examination.
数年来频繁使用振动工具可能导致手指血液循环的神经血管紊乱,并引发典型的雷诺现象,振动和/或寒冷暴露会诱发发作。这种情况被认定为一种职业病,称为振动性白指(VWF)。本研究的目的是评估红外热成像(IRT)结合冷激发试验在诊断VWF患者雷诺现象中的作用。
将24例经其他方法确诊为VWF的患者与12例匹配的对照受试者进行比较。在双手暴露于12摄氏度水浴3分钟之前、之后以及之后5、10、15、20和30分钟时,同时对双手进行IRT测量。分析所有手指的温度测量结果,并记录所有手指完全复温的时间。
两组的基础热成像图无差异,而VWF患者冷暴露后的平均手指温度明显低于对照组,两组之间存在相当大的个体重叠。因此,在个体病例中,测定绝对手指温度并非有用的诊断工具,但可能有助于药理学研究(组分析)。与绝对手指温度不同,冷暴露后的复温时间参数在个体基础上具有诊断价值:15分钟后完全复温表明血管反应正常,冷激发后30分钟复温不完全表明由于VWF导致血管反应受损。
IRT是诊断VWF患者雷诺现象的有用工具,并提供了适合进一步随访检查的充分记录。