Schieker M, Heiss C, Mutschler W
Chirurgische Klinik und Poliklinik Innenstadt, Klinikum, Ludwig-Maximilians-Universität München, Nussbaumstrasse 20, 80336 München.
Unfallchirurg. 2008 Aug;111(8):613-9; quiz 620. doi: 10.1007/s00113-008-1489-6.
Bone substitutes are used to supplement or substitute autogenous transplantation of cancellous bone. These materials should provide a scaffold structure and support bone healing alone or in combination with other substances. In trauma surgery the indication for use of bone substitutes lies mostly in filling of small metaphyseal cancellous bone defects with high vascularization following fracture. In comparison to transplantation of cancellous bone, the advantages of bone substitutes are sufficient availability without additional donor site morbidity. Moreover, biomaterials can be stored, also ensuring ready availability. This educational article gives an overview of bone substitutes currently in clinical use.
骨替代物用于补充或替代松质骨的自体移植。这些材料应提供支架结构,并单独或与其他物质结合支持骨愈合。在创伤外科手术中,骨替代物的使用指征主要在于填充骨折后血运丰富的小干骺端松质骨缺损。与松质骨移植相比,骨替代物的优点是供应充足,且不会增加供区并发症。此外,生物材料可以储存,也能确保随时可用。这篇教育性文章概述了目前临床使用的骨替代物。