Karwinski B, Svendsen E
Department of Pathology, Gade Institute, University of Bergen, Norway.
APMIS. 1989 Nov;97(11):1018-24. doi: 10.1111/j.1699-0463.1989.tb00512.x.
A review of 8571 autopsies disclosed 2833 patients with malignant tumours from 1975 to 1984 at the Department of Pathology, The Gade Institute. Cardiac metastases were found in 130 cases. An increase of cardiac involvement was shown in the autopsy material from 1.2% in 1975-1979 to 1.8% in 1980-1984. The same trend was seen if cardiac metastases were related to malignant tumours. Numerically, lung cancer accounted for most of the metastases seen, but the increase was made up by other tumours than lung cancer. especially malignant melanoma, mesothelioma, breast cancer and sarcomas. These tumours have a high frequency of heart metastases and the increased incidence of these cancers in the material explains the rise of cardiac metastases. Cardiac metastases increased with rising number of distant metastases. This study shows that mesotheliomas have the highest percentage of cardiac spread. The importance of autopsy for detecting metastatic spread in sites that are difficult to detect clinically is emphasized.
对8571例尸检进行回顾发现，1975年至1984年期间，在加德研究所病理科有2833例患有恶性肿瘤的患者。发现130例有心脏转移。尸检材料显示心脏受累情况有所增加，从1975 - 1979年的1.2%增至1980 - 1984年的1.8%。如果将心脏转移与恶性肿瘤相关联，也呈现相同趋势。从数量上看，肺癌占所见转移的大部分，但增长是由肺癌以外的其他肿瘤引起的，尤其是恶性黑色素瘤、间皮瘤、乳腺癌和肉瘤。这些肿瘤发生心脏转移的频率很高，材料中这些癌症发病率的增加解释了心脏转移的上升。心脏转移随着远处转移数量的增加而增加。本研究表明间皮瘤的心脏转移百分比最高。强调了尸检对于检测临床上难以发现部位的转移扩散的重要性。
