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2
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本文引用的文献

1
Protease inhibitors from several classes work synergistically against Callosobruchus maculatus.来自几类的蛋白酶抑制剂协同作用对抗绿豆象。
J Insect Physiol. 2007 Jul;53(7):734-40. doi: 10.1016/j.jinsphys.2007.03.008. Epub 2007 Mar 30.
2
The HopX (AvrPphE) family of Pseudomonas syringae type III effectors require a catalytic triad and a novel N-terminal domain for function.丁香假单胞菌III型效应蛋白的HopX（AvrPphE）家族发挥功能需要一个催化三联体和一个新的N端结构域。
Mol Plant Microbe Interact. 2007 Apr;20(4):346-57. doi: 10.1094/MPMI-20-4-0346.
3
Indirect activation of a plant nucleotide binding site-leucine-rich repeat protein by a bacterial protease.细菌蛋白酶对植物核苷酸结合位点富含亮氨酸重复序列蛋白的间接激活作用
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2531-6. doi: 10.1073/pnas.0608779104. Epub 2007 Feb 2.
4
A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease.一种致病疫霉半胱氨酸蛋白酶抑制剂样蛋白作用于一种新的番茄类木瓜蛋白酶胞外蛋白酶。
Plant Physiol. 2007 Jan;143(1):364-77. doi: 10.1104/pp.106.090050. Epub 2006 Nov 3.
5
Meloidogyne incognita: molecular and biochemical characterisation of a cathepsin L cysteine proteinase and the effect on parasitism following RNAi.南方根结线虫：组织蛋白酶L半胱氨酸蛋白酶的分子与生化特性以及RNA干扰后对寄生作用的影响
Exp Parasitol. 2007 Feb;115(2):114-20. doi: 10.1016/j.exppara.2006.07.008. Epub 2006 Sep 22.
6
Eukaryotic cyclophilin as a molecular switch for effector activation.真核亲环素作为效应器激活的分子开关。
Mol Microbiol. 2006 Sep;61(6):1485-96. doi: 10.1111/j.1365-2958.2006.05335.x.
7
Subterfuge and manipulation: type III effector proteins of phytopathogenic bacteria.诡计与操控：植物致病细菌的III型效应蛋白
Annu Rev Microbiol. 2006;60:425-49. doi: 10.1146/annurev.micro.60.080805.142251.
8
Effects of mechanical wounding on Carica papaya cysteine endopeptidases accumulation and activity.
Int J Biol Macromol. 2006 May 30;38(3-5):216-24. doi: 10.1016/j.ijbiomac.2006.02.021. Epub 2006 Apr 3.
9
Membrane release and destabilization of Arabidopsis RIN4 following cleavage by Pseudomonas syringae AvrRpt2.丁香假单胞菌AvrRpt2切割后拟南芥RIN4的膜释放与去稳定化
Mol Plant Microbe Interact. 2005 Dec;18(12):1258-68. doi: 10.1094/MPMI-18-1258.
10
MEROPS: the peptidase database.MEROPS：肽酶数据库。
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D270-2. doi: 10.1093/nar/gkj089.

木瓜蛋白酶样半胱氨酸蛋白酶：植物及其入侵者在分子战场上的关键参与者。

Papain-like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders.

作者信息

Shindo Takayuki, Van der Hoorn Renier A L

机构信息

Plant Chemetics Laboratory, Max Planck Institute for Plant Breeding Research, Carl-von-Linne Weg 10, 50829 Cologne, Germany.

出版信息

Mol Plant Pathol. 2008 Jan;9(1):119-25. doi: 10.1111/j.1364-3703.2007.00439.x.

DOI:10.1111/j.1364-3703.2007.00439.x
PMID:18705889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6640327/
Abstract

Papain-like cysteine proteases (PLCPs) play crucial roles in plant-pathogen/pest interactions. During these parasitic interactions, PLCPs act on non-self substrates, provoking the selection of counteracting inhibitors and other means to evade proteolysis. We review examples of PLCPs acting on molecular battlefields in the extracellular space, plant cytoplasm and herbivore gut. Examples are maize Mir1 (Maize inbred resistance 1), tomato Rcr3 (Required for Cladosporium resistance-3), Pseudomonas AvrRpt2 and AurPphB, insect DvCAL1 (Diabrotica virgifera cathepsin L-like protease-1) and nematode MiCpl1 (Meloidogyne incognita cathepsin L-like protease 1). The data suggest that PLCPs cleave specific proteins and that their translocation, activation and inhibition of PLCPs are tightly regulated.

摘要

木瓜蛋白酶样半胱氨酸蛋白酶（PLCPs）在植物与病原体/害虫的相互作用中发挥着关键作用。在这些寄生相互作用过程中，PLCPs作用于非自身底物，促使对抗性抑制剂的选择以及其他逃避蛋白水解的方式。我们综述了PLCPs在细胞外空间、植物细胞质和食草动物肠道等分子战场中发挥作用的实例。例如玉米的Mir1（玉米自交系抗性1）、番茄的Rcr3（抗枝孢属菌-3所需蛋白）、丁香假单胞菌的AvrRpt2和AurPphB、昆虫的DvCAL1（玉米根萤叶甲组织蛋白酶L样蛋白酶-1）以及线虫的MiCpl1（南方根结线虫组织蛋白酶L样蛋白酶1）。数据表明，PLCPs可切割特定蛋白质，并且它们的转运、激活及对PLCPs的抑制受到严格调控。