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接受长期血液透析的老年患者的视力损害

Visual impairment in elderly patients receiving long-term hemodialysis.

作者信息

Chiu Ernest, Markowitz Samuel N, Cook Wendy L, Jassal Sarbjit V

机构信息

Nephrology Division, University Health Network, Toronto, Ontario, Canada.

出版信息

Am J Kidney Dis. 2008 Dec;52(6):1131-8. doi: 10.1053/j.ajkd.2008.05.032. Epub 2008 Aug 15.

Abstract

BACKGROUND

Visual impairments are associated with low quality of life, impairment of daily activities, and accidental falls. As dialysis patients are increasingly older and more disabled, we sought to assess visual impairments within an elderly dialysis population. Based on data from the general population, we hypothesized that more than 30% of dialysis patients 65 years or older would have visual impairment manifested by loss of visual acuity, depth perception, or contrast sensitivity.

STUDY DESIGN

Single-center cross-sectional study.

SETTING & PARTICIPANTS: Patients established on hemodialysis therapy, age older than 65 years.

OUTCOMES

The proportion of elderly hemodialysis patients with impairments in visual acuity, contrast sensitivity, and depth perception.

MEASUREMENTS

Lighthouse Near Visual Acuity Test, Lea Screener contrast sensitivity test (Goodlite, MA, USA), Titmus Stereotest, Folstein Mini-Mental Status Examination.

RESULTS

152 of 159 patients (95.6%) had visual acuity levels less than age-expected values. Under North American (American Medical Association, edition 4) guidelines for disability compensation, 62 patients (39.0%) fulfilled criteria for legal blindness. Sixty patients (37.0%) had poor contrast sensitivity and 48 (30.6%) failed the Housefly component of the Titmus Stereotest. Failing the Housefly component was associated with a lower Folstein Mini-Mental Status Examination score (23.4 +/- 4.2 v 25.1 +/- 3.5; P = 0.01).

LIMITATIONS

This study is limited by the cross-sectional study design and abbreviated test protocol used for vision assessment.

CONCLUSIONS

Results of this study suggest that elderly hemodialysis patients have a high frequency of visual impairment. Formal low vision assessment and low vision rehabilitation may be useful in elderly dialysis patients. Additional study is required to determine whether the absence of depth perception in this patient group is associated with deteriorating cognitive function.

摘要

背景

视力障碍与生活质量低下、日常活动受限及意外跌倒相关。随着透析患者年龄增长且残疾程度增加,我们试图评估老年透析人群中的视力障碍情况。基于普通人群的数据,我们推测65岁及以上的透析患者中,超过30%会出现因视力、深度感知或对比敏感度丧失而导致的视力障碍。

研究设计

单中心横断面研究。

研究地点及参与者

接受血液透析治疗、年龄大于65岁的患者。

研究结果

老年血液透析患者中视力、对比敏感度和深度感知受损的比例。

测量方法

灯塔近视力测试、Lea Screener对比敏感度测试(美国马萨诸塞州Goodlite公司)、Titmus立体视觉测试、Folstein简易精神状态检查表。

结果

159例患者中有152例(95.6%)视力水平低于预期年龄值。根据北美(美国医学协会第4版)残疾补偿指南,62例患者(39.0%)符合法定失明标准。60例患者(37.0%)对比敏感度较差,48例(30.6%)Titmus立体视觉测试中家蝇部分未通过。家蝇部分未通过与Folstein简易精神状态检查表得分较低相关(23.4±4.2对25.1±3.5;P=0.01)。

局限性

本研究受横断面研究设计及用于视力评估的简化测试方案限制。

结论

本研究结果表明老年血液透析患者视力障碍发生率较高。正式的低视力评估和低视力康复对老年透析患者可能有用。需要进一步研究以确定该患者群体中深度感知缺失是否与认知功能恶化有关。

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