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功能性神经障碍:老问题,新视角。

Functional Neurological Disorder-Old Problem New Perspective.

机构信息

"Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

"Dr. Victor Gomoiu" Children's Hospital, 022102 Bucharest, Romania.

出版信息

Int J Environ Res Public Health. 2023 Jan 8;20(2):1099. doi: 10.3390/ijerph20021099.

Abstract

Functional neurological disorder (FND) is a common issue in the pediatric population. The concept and our understanding of functional neurological disorders have changed over the past years, and new etiologic models and treatment plans have been explored. Knowledge about FND in the pediatric population, however, is lacking. The aim of this review is to provide an update on pediatric functional neurological disorder. We conducted a literature search of PubMed and SCOPUS databases and reviewed a total of 85 articles to gain insight into the current understanding of FND etiology, diagnosis, treatment, and prognosis in children and adolescents. Functional and high resolution MRI revealed abnormal connectivity and structural changes in patients with functional symptoms. The diagnostic criteria no longer require the presence of a psychological factor and instead focus on a rule-in diagnosis. Treatment of FND includes a clear communication of the diagnosis and the support of a multidisciplinary team. Although FND typically has a poor prognosis, better outcomes appear to have been achieved in children and young adults. We conclude that pediatric functional neurological disorder is a prevalent pathology and that this patient population has additional specific needs compared to the adult population.

摘要

功能性神经障碍(FND)是儿科人群中的常见问题。近年来,我们对功能性神经障碍的概念和理解发生了变化,同时也探索了新的病因模型和治疗方案。然而,我们对儿科人群中的 FND 知之甚少。本综述旨在提供有关儿科功能性神经障碍的最新信息。我们对 PubMed 和 SCOPUS 数据库进行了文献检索,共查阅了 85 篇文章,以深入了解儿童和青少年 FND 的病因、诊断、治疗和预后的最新认识。功能和高分辨率 MRI 显示功能性症状患者的连接和结构异常。诊断标准不再需要存在心理因素,而是侧重于明确诊断。FND 的治疗包括明确诊断并支持多学科团队。尽管 FND 的预后通常较差,但儿童和青少年的预后似乎更好。我们得出结论,儿科功能性神经障碍是一种普遍存在的疾病,与成人患者相比,该患者群体有额外的特定需求。

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