Ngoan Le Tran, Anh Nguyen Thi Diep, Huong Nguyen Thi Thanh, Thu Nguyen Thi, Lua Nguyen Thi, Hang Lai Thi Minh, Bich Nguyen Ngoc, Hieu Nguyen Van, Quyet Ha Van, Tai Le Thi, Van Do Duc, Khan Nguyen Cong, Mai Le Bach, Tokudome Shinkan, Yoshimura Takesumi
Dept. of Occupational Health, Hanoi Medical University, Ton That Tung Street, Hanoi, Viet Nam.
Asian Pac J Cancer Prev. 2008 Apr-Jun;9(2):299-302.
The International Collaborative Epidemiological Study of Host and Environmental Factors for Stomach and Colorectal Cancers in Southeast Asian Countries (SEACs) has been conducted in Viet Nam from 2003 to 2008 on a case-control basis. For further effective primary prevention, we examined gastric and colorectal cancer mortality nationwide in eight regions of Viet Nam in 2005-06.
Both demographic data and lists of all deaths in 2005-06 were obtained from all 10,769 commune health stations in Viet Nam. Five indicators included name, age, sex, date of death and cause of death was collected for each case. We selected only communes having the list of deaths with clear cause for each case and crude mortality rate for all causes from 300-600/100,000 as published by the Ministry of Health for a reasonable accuracy and completeness. Obtained data for all causes, all cancers, stomach and colorectal cancer deaths as well as demographic information were processed using Excel software and exported to STATA 8.0 for estimation of world age-standardized cancer mortality rates per 100,000.
Data were available for 1,246 gastric cases, (819 male and 427 female) with age-standardized mortality rates from 12.7 to 31.3 per 100,000 in males and from 5.9 to 10.3 per 100,000 in females in the 8 regions of the country. For colorectal cancers, 542 cases (268 male and 274 female) gave mortality rates from 4.0 to 11.3 per 100,000 in males and from 3.0 to 7.8 per 100,000 in females.
Stomach cancer mortality in males in the region of North East in the North Viet Nam (2005-06) was higher than that in Japan (2002) (31.3 versus 28.7 per 100,000) while colorectal cancer in Viet Nam was lower. While prevalence of Helicobacter pyloris infection in Viet Nam was from 70-75% in both males and females, the stomach cancer rate in males was significantly higher than in females, 31.3 versus 6.8 per 100,000, suggesting an influence of other environmental risk factors. Whether protective factors are operating against colorectal cancer in Viet Nam now needs to be explored.
东南亚国家胃癌和结直肠癌宿主与环境因素国际协作流行病学研究（SEACs）于2003年至2008年在越南以病例对照的方式开展。为了进一步进行有效的一级预防，我们于2005 - 2006年在越南的八个地区对全国胃癌和结直肠癌死亡率进行了调查。
人口统计数据和2005 - 2006年所有死亡人员名单均来自越南所有10769个公社卫生站。为每个病例收集了五个指标，包括姓名、年龄、性别、死亡日期和死因。我们仅选择那些每个病例死因明确且全死因粗死亡率在卫生部公布的300 - 600/10万之间的公社，以确保合理的准确性和完整性。使用Excel软件对所有死因、所有癌症、胃癌和结直肠癌死亡数据以及人口统计信息进行处理，并导出到STATA 8.0中，以估算每10万人的世界年龄标准化癌症死亡率。
在该国八个地区，有1246例胃癌病例的数据可用（男性819例，女性427例），男性年龄标准化死亡率为每10万人12.7至31.3例，女性为每10万人5.9至10.3例。对于结直肠癌，有542例病例（男性268例，女性274例），男性死亡率为每10万人4.0至11.3例，女性为每10万人3.0至7.8例。
越南北部东北部地区男性胃癌死亡率（2005 - 2006年）高于日本（2002年）（每10万人31.3例对28.7例），而越南的结直肠癌死亡率则较低。虽然越南男女幽门螺杆菌感染率均为70 - 75%，但男性胃癌发病率明显高于女性，每10万人31.3例对6.8例，这表明存在其他环境危险因素的影响。越南目前是否存在针对结直肠癌的保护因素尚需探索。
