Younes Riad Naim
Hospital Sírio-Libanês, São Paulo, SP.
Rev Assoc Med Bras (1992). 2008 Jul-Aug;54(4):305-7. doi: 10.1590/s0104-42302008000400014.
Neuroendocrine tumors (NET) can originate diffusely in most organs, with varying clinical presentations. The relative rarity of these tumors, previously referred to as carcinoids, encouraged several centers worldwide to study NET. Since 2003, a similar group was established in , the GETNE - Grupo de Estudo de Tumores Neuroendocrinos (Neuroendocrine Tumors Study Group) that included 32 centers, from all regions of Brasil. A patient database was initiated, collecting information about NET, regardless of the site of origin.
The present study shows initial results of 1000 patients included.
Descriptive statistical analyses, as well as overall survival rates for different groups of NET patients registered by GETNE.
Most patients presented with thoracic NET (71.6%), while 20.2% had gastro-entero-pancreatic tumors. Median follow-up of all patients included was 33.7 months (range 1-141 months). At the time of the analysis, 29.3% of the patients were still alive (of these, 45.7% were alive with no evidence of disease).
This is the largest database of NET in, and further accrual of new patients, as well as individual study results are expected in the near future.
神经内分泌肿瘤（NET）可在大多数器官中弥漫性起源，临床表现各异。这些肿瘤（以前称为类癌）相对罕见，促使全球多个中心对NET进行研究。自2003年以来，在巴西成立了一个类似的小组，即GETNE - 神经内分泌肿瘤研究小组（Grupo de Estudo de Tumores Neuroendocrinos），其中包括来自巴西各个地区的32个中心。启动了一个患者数据库，收集有关NET的信息，无论其起源部位如何。
本研究展示了纳入的1000例患者的初步结果。
进行描述性统计分析，以及GETNE登记的不同组NET患者的总生存率分析。
大多数患者表现为胸段NET（71.6%），而20.2%患有胃肠胰肿瘤。纳入的所有患者的中位随访时间为33.7个月（范围1 - 141个月）。在分析时，29.3%的患者仍然存活（其中45.7%存活且无疾病证据）。
这是巴西最大的NET数据库，预计在不久的将来会有更多新患者加入以及个体研究结果。
