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土曲霉性心肌炎:一例报告及文献复习

Aspergillus terreus myocarditis: report of a case and review of the literature.

作者信息

Russack V

机构信息

Department of Pathology, University of California, San Diego.

出版信息

Am J Cardiovasc Pathol. 1990;3(3):275-9.

PMID:2095835
Abstract

Aspergillus terreus is an uncommon cause of myocarditis, with only six reported cases in the world literature. This report describes a case of severe disseminated Aspergillus terreus infection with extensive involvement of the heart in an immunosuppressed patient after aortic valve replacement surgery. Pathologic findings are similar to those found in Aspergillus fumigatus myocarditis. All six previously reported cases of A. terreus carditis occurred in postoperative cardiac surgery or immunocompromised patients. This pathogen should not be dismissed as simply a colonizing organism or a contaminant in fungal cultures, particularly those from hospitalized or seriously ill patients.

摘要

土曲霉是心肌炎的一种罕见病因,世界文献中仅报道过6例。本报告描述了1例主动脉瓣置换术后免疫抑制患者发生严重播散性土曲霉感染且心脏广泛受累的病例。病理结果与烟曲霉心肌炎相似。先前报道的所有6例土曲霉性心内膜炎病例均发生于心脏手术后或免疫功能低下的患者。这种病原体不应仅仅被视为真菌培养中的定植菌或污染物,尤其是来自住院患者或重症患者的培养物。

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引用本文的文献

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In vitro activities of amphotericin B and voriconazole against aleurioconidia from Aspergillus terreus.两性霉素B和伏立康唑对土曲霉粉孢子的体外活性。
Antimicrob Agents Chemother. 2005 Jun;49(6):2539-40. doi: 10.1128/AAC.49.6.2539-2540.2005.
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In vitro analyses, animal models, and 60 clinical cases of invasive Aspergillus terreus infection.体外分析、动物模型以及60例土曲霉侵袭性感染的临床病例。
Antimicrob Agents Chemother. 2004 Sep;48(9):3217-25. doi: 10.1128/AAC.48.9.3217-3225.2004.
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Bilateral pulmonary aspergilloma caused by an atypical isolate of Aspergillus terreus.
由土曲霉非典型分离株引起的双侧肺曲菌球
J Clin Microbiol. 2000 May;38(5):2010-4. doi: 10.1128/JCM.38.5.2010-2014.2000.
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J Clin Microbiol. 1999 Jul;37(7):2343-5. doi: 10.1128/JCM.37.7.2343-2345.1999.
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Endocarditis and aortal embolization caused by Aspergillus terreus in a patient with acute lymphoblastic leukemia in remission: diagnosis by peripheral-blood culture.缓解期急性淋巴细胞白血病患者由土曲霉引起的心内膜炎和主动脉栓塞:通过外周血培养进行诊断
J Clin Microbiol. 1998 Nov;36(11):3347-51. doi: 10.1128/JCM.36.11.3347-3351.1998.
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Aspergillosis in children with acquired immune deficiency.获得性免疫缺陷儿童的曲霉病
Pediatr Radiol. 1993;23(6):492-4. doi: 10.1007/BF02012466.