Carballo M, Muñoz M J
Department of Animal Health, CIT-I.N.I.A., Madrid, Spain.
Appl Environ Microbiol. 1991 Jun;57(6):1813-6. doi: 10.1128/aem.57.6.1813-1816.1991.
The effects of sublethal concentrations of a variety of chemicals on the susceptibility of rainbow trout (Oncorhynchus mykiss) juveniles to Saprolegnia parasitica infection was examined. Sublethal concentrations of un-ionized ammonia (0.05 mg/liter) and nitrite (0.12 mg/liter) increased fish susceptibility after 10 days of exposure to the toxin, this increase being higher for ammonia (75% and 20% morbidity) than for nitrite (20% and 0% morbidity, respectively) with inoculum doses of 1.4 x 10(6) and 9.5 x 10(5) zoospores per liter, respectively. Sublethal concentrations of copper (0.05 mg/liter) or cyanide (0.05 mg/liter) did not show enhancement of infection by S. parasitica, even though the toxin exposure was for 21 days and the inoculum doses were higher than those for the experiments with the nitrogen compounds (4 x 10(6) and 3.2 x 10(6) zoospores per liter. However, infections began to appear in control animals.
研究了多种化学物质的亚致死浓度对虹鳟(Oncorhynchus mykiss)幼鱼感染寄生水霉(Saprolegnia parasitica)易感性的影响。暴露于毒素10天后,未电离氨(0.05毫克/升)和亚硝酸盐(0.12毫克/升)的亚致死浓度增加了鱼类的易感性,对于氨(发病率分别为75%和20%),这种增加高于亚硝酸盐(发病率分别为20%和0%),接种剂量分别为每升1.4×10⁶和9.5×10⁵个游动孢子。铜(0.05毫克/升)或氰化物(0.05毫克/升)的亚致死浓度未显示出寄生水霉感染的增强,尽管毒素暴露时间为21天且接种剂量高于氮化合物实验(每升4×10⁶和3.2×10⁶个游动孢子)。然而,对照动物开始出现感染。