Pauls A M, Lautenbacher S, Strian F, Pirke K M, Krieg J C
Max-Planck-Institut für Psychiatrie, Klinisches Institut, Munich, Federal Republic of Germany.
Eur Arch Psychiatry Clin Neurosci. 1991;241(1):8-12. doi: 10.1007/BF02193748.
The somatosensory functions of small-diameter nerve fibres were tested on the lower and upper extremities in nine patients with anorexia nervosa, ten patients with bulimia nervosa and ten control subjects, by analysing warmth, cold, and pain thresholds. To test large-diameter nerve fibres, the vibration threshold was also measured. Both patient groups had markedly elevated pain thresholds compared with the control subjects. In contrast, warmth and cold thresholds were only suggestively elevated while vibration thresholds were not at all increased in the patients. A distal-proximal pattern of somatosensory deficits, suggestive of peripheral polyneuropathy, was not observed. Hence, a peripheral polyneuropathy affecting small or large afferent fibres as a consequence of an eating disorder seems to be a rare event.
通过分析热、冷和疼痛阈值，对9名神经性厌食症患者、10名神经性贪食症患者和10名对照受试者的下肢和上肢小直径神经纤维的躯体感觉功能进行了测试。为了测试大直径神经纤维，还测量了振动阈值。与对照受试者相比，两组患者的疼痛阈值均显著升高。相比之下，患者的热阈值和冷阈值仅呈提示性升高，而振动阈值则完全没有升高。未观察到提示周围性多发性神经病的躯体感觉缺陷的远端-近端模式。因此，进食障碍导致影响小或大传入纤维的周围性多发性神经病似乎是一种罕见的情况。
