Debruyckere G, Van Peteghem C
Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, State University of Ghent, Belgium.
J Chromatogr. 1991 Apr 5;564(2):393-403. doi: 10.1016/0378-4347(91)80508-a.
The metabolism of 19-nortestosterone was investigated in a miniature non-castrated male pig (boar), in a castrated pig (barrow) and in a female pig (sow). Urine samples were taken before and at regular intervals after the injection of 100 mg of Laurabolin (nortestosterone laurate). The sample clean-up consists in preliminary solid-phase extraction, followed by high-performance liquid chromatographic purification and fractionation. Finally, gas chromatography-mass spectrometry is used to identify the 19-nortestosterone metabolites.
在小型未阉割雄性猪（公猪）、阉割猪（阉猪）和雌性猪（母猪）中研究了19-去甲睾酮的代谢情况。在注射100毫克劳勃林（月桂酸诺龙）之前及之后定期采集尿液样本。样本净化包括初步的固相萃取，随后进行高效液相色谱纯化和分离。最后，使用气相色谱-质谱联用技术鉴定19-去甲睾酮的代谢产物。
