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2011 - 2015年波兰屠宰动物组织中合成代谢激素残留的控制

Control of Anabolic Hormone Residues in Tissues of Slaughter Animals in Poland During the Period of 2011-2015.

作者信息

Iwona Matraszek-Żuchowska, Barbara Woźniak, Alicja Kłopot, Sebastian Witek, Katarzyna Sielska, Andrzej Posyniak

机构信息

Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland.

出版信息

J Vet Res. 2017 Apr 4;61(1):69-79. doi: 10.1515/jvetres-2017-0009. eCollection 2017 Mar.

Abstract

INTRODUCTION

Studies of anabolic hormone residues in the tissues of slaughter animals have been carried out in Poland for more than 25 years. During the period of 2011 to 2015, a total of 35 387 samples from different animal species were tested in the National Residue Control Programme for the presence of residues of compounds that cause hormonal effects, as listed in Annex 1 of Directive 96/23/EC.

MATERIAL AND METHODS

The research was conducted in the National Reference Laboratory and eight regional laboratories in departments of veterinary hygiene located throughout the country. Urine, muscle tissue, serum, kidney fat, and drinking water were the targeted matrices. Test methods based on instrumental techniques such as gas and liquid chromatography coupled with mass spectrometry were applied, as well as enzyme-linked immunosorbent assays (ELISA).

RESULTS

The concentration of detected hormones exceeded the decision limits in 30 samples, the consequence of which was 41 non-compliances with current applicable criteria. The hormones found present pseudo-endogenous (nortestosterone and boldenone) only, while synthetic hormones were not identified.

CONCLUSION

The non-compliant findings constitute a small percentage (0.085%) of the five-year analysis compilation. On this basis the related food produced in Poland can be accepted as safe for human consumption with regard to the hormone residues tested.

摘要

引言

在波兰,对屠宰动物组织中的合成代谢激素残留进行的研究已开展了25年多。在2011年至2015年期间,国家残留控制计划共检测了来自不同动物物种的35387份样本,以检测是否存在欧盟理事会96/23/EC号指令附件1中所列的具有激素作用的化合物残留。

材料与方法

研究在国家参考实验室以及遍布全国的八个位于兽医卫生部门的区域实验室进行。尿液、肌肉组织、血清、肾周脂肪和饮用水是目标基质。采用了基于仪器技术的检测方法,如气相色谱和液相色谱与质谱联用,以及酶联免疫吸附测定法(ELISA)。

结果

在30份样本中检测到的激素浓度超过了判定限度,结果导致41项不符合现行适用标准的情况。所发现的激素仅为伪内源性激素(诺龙和勃地酮),未鉴定出合成激素。

结论

不符合规定的检测结果在五年分析汇总中占比很小(0.085%)。基于此,就所检测的激素残留而言,波兰生产的相关食品可被认为对人类消费是安全的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5d/5894401/1b6f22dad676/jvetres-61-069-g001.jpg

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