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一名现役空军高级飞行员的Brugada综合征

Brugada syndrome in an active duty Air Force senior pilot.

作者信息

Walker Dennis D, Johnson Monica L, Craig-Gray Robert W, Loyd Frank

机构信息

Element Leader/FSO, 697 Louisiana Drive, Dyess AFB, TX 79607, USA.

出版信息

Mil Med. 2008 Aug;173(8):809-13. doi: 10.7205/milmed.173.8.809.

Abstract

INTRODUCTION

Brugada syndrome describes a subgroup of patients at risk for polymorphic ventricular tachycardia, ventricular fibrillation, and sudden cardiac death and is likely underdiagnosed among aviators.

CASE REPORT

A 40-year-old male pilot presented to the clinic for his physical. He denied any symptoms on initial questioning. Subsequent electrocardiogram (ECG) revealed premature ventricular couplets with ST-segment elevation in V1 and V2 of the precordial leads with T-wave abnormalities.

DISCUSSION

Special care must be taken if ECG demonstrates a Brugada pattern-especially in patients with a history of syncope or a family history of sudden death. Recent studies have confirmed a significant risk reduction in symptomatic patients with type 1 Brugada to as low as 0.8% to 3% with an implantable cardioverter defibrillator.

CONCLUSION

Symptomatic patients displaying type 1 Brugada ECG (spontaneous or after sodium channel blockade) should receive an implantable cardioverter defibrillator and must be permanently disqualified. The Aeromedical Consultation Service should review all cases of Brugada syndrome and render a return to fly for asymptomatic nondiagnostic Brugada types.

摘要

引言

Brugada综合征描述了一组有发生多形性室性心动过速、心室颤动和心源性猝死风险的患者,在飞行员中可能存在诊断不足的情况。

病例报告

一名40岁男性飞行员前来诊所进行体检。初诊时他否认有任何症状。随后的心电图(ECG)显示室性早搏二联律,胸前导联V1和V2导联ST段抬高伴T波异常。

讨论

如果心电图显示出Brugada波形,必须格外小心——尤其是有晕厥病史或猝死家族史的患者。最近的研究证实,植入式心脏复律除颤器可将1型Brugada综合征有症状患者的显著风险降低至0.8%至3%。

结论

表现出1型Brugada心电图(自发或钠通道阻滞后)的有症状患者应接受植入式心脏复律除颤器治疗,并且必须永久取消飞行资格。航空医学咨询服务部门应审查所有Brugada综合征病例,并对无症状的非诊断性Brugada类型做出恢复飞行的决定。

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