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右侧和左侧顶叶后皮质中对显著信息的反射性和预备性选择与抑制

Reflexive and preparatory selection and suppression of salient information in the right and left posterior parietal cortex.

作者信息

Mevorach Carmel, Humphreys Glyn W, Shalev Lilach

机构信息

School of Psychology, University of Birmingham, Edgbaston, Birmingham, UK.

出版信息

J Cogn Neurosci. 2009 Jun;21(6):1204-14. doi: 10.1162/jocn.2009.21088.


DOI:10.1162/jocn.2009.21088
PMID:18752407
Abstract

Attentional cues can trigger activity in the parietal cortex in anticipation of visual displays, and this activity may, in turn, induce changes in other areas of the visual cortex, hence, implementing attentional selection. In a recent TMS study [Mevorach, C., Humphreys, G. W., & Shalev, L. Opposite biases in salience-based selection for the left and right posterior parietal cortex. Nature Neuroscience, 9, 740-742, 2006b], it was shown that the posterior parietal cortex (PPC) can utilize the relative saliency (a nonspatial property) of a target and a distractor to bias visual selection. Furthermore, selection was lateralized so that the right PPC is engaged when salient information must be selected and the left PPC when the salient information must be ignored. However, it is not clear how the PPC implements these complementary forms of selection. Here we used on-line triple-pulse TMS over the right or left PPC prior to or after the onset of global/local displays. When delivered after the onset of the display, TMS to the right PPC disrupted the selection of the more salient aspect of the hierarchical letter. In contrast, left PPC TMS delivered prior to the onset of the stimulus disrupted responses to the lower saliency stimulus. These findings suggest that selection and suppression of saliency, rather than being "two sides of the same coin," are fundamentally different processes. Selection of saliency seems to operate reflexively, whereas suppression of saliency relies on a preparatory phase that "sets up" the system in order to effectively ignore saliency.

摘要

注意线索能够在预期视觉呈现时触发顶叶皮质的活动,而这种活动反过来可能会引起视觉皮质其他区域的变化,从而实现注意选择。在最近一项经颅磁刺激(TMS)研究中[梅沃拉赫、C.、汉弗莱斯、G. W. 和沙莱夫、L. 基于显著性的左右后顶叶皮质选择中的相反偏差。《自然神经科学》,9,740 - 742,2006b],研究表明后顶叶皮质(PPC)能够利用目标和干扰项的相对显著性(一种非空间属性)来偏向视觉选择。此外,选择具有偏向性,即当必须选择显著信息时右侧PPC会参与,而当必须忽略显著信息时左侧PPC会参与。然而,目前尚不清楚PPC是如何实现这些互补的选择形式的。在这里,我们在全局/局部呈现开始之前或之后,对右侧或左侧PPC施加在线三脉冲TMS。当在呈现开始后施加时,对右侧PPC的TMS干扰了对层级字母中更显著方面的选择。相比之下,在刺激开始前对左侧PPC施加TMS则干扰了对较低显著性刺激的反应。这些发现表明,显著性的选择和抑制并非“同一枚硬币的两面”,而是根本不同的过程。显著性的选择似乎是自动进行的,而显著性的抑制则依赖于一个准备阶段,该阶段“设定”系统以便有效地忽略显著性。

相似文献

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Reflexive and preparatory selection and suppression of salient information in the right and left posterior parietal cortex.

J Cogn Neurosci. 2009-6

[2]
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[6]
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[10]
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