Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany.
Sci Rep. 2022 Mar 16;12(1):4530. doi: 10.1038/s41598-022-08510-8.
The neurophysiological processes underlying the inhibition of impulsive responses have been studied extensively. While also the role of theta oscillations during response inhibition is well examined, the relevance of resting-state theta activity for inhibitory control processes is largely unknown. We test the hypothesis that there are specific relationships between resting-state theta activity and sensory/motor coding levels during response inhibition using EEG methods. We show that resting theta activity is specifically linked to the stimulus-related fraction of neurophysiological activity in specific time windows during motor inhibition. In contrast, concomitantly coded processes related to decision-making or response selection as well as the behavioral inhibition performance were not associated with resting theta activity. Even at the peak of task-related theta power, where task-related theta activity and resting theta activity differed the most, there was still predominantly a significant correlation between both types of theta activity. This suggests that aspects similar to resting dynamics are evident in the proportion of inhibition-related neurophysiological activity that reflects an "alarm" signal, whose function is to process and indicate the need for cognitive control. Thus, specific aspects of task-related theta power may build upon resting theta activity when cognitive control is necessary.
抑制冲动反应的神经生理过程已经得到了广泛的研究。虽然在反应抑制过程中θ 振荡的作用也得到了很好的检验，但静息态θ 活动对于抑制控制过程的相关性在很大程度上仍是未知的。我们使用 EEG 方法检验了这样一个假设，即静息态θ 活动与反应抑制过程中的感觉/运动编码水平之间存在特定的关系。我们发现，静息态θ 活动与运动抑制过程中特定时间窗口内与刺激相关的神经生理活动分数特异性相关。相比之下，与决策或反应选择相关的同时编码过程以及行为抑制表现与静息态θ 活动没有关联。即使在与任务相关的 θ 功率峰值时，与任务相关的 θ 活动和静息态θ 活动之间的差异最大，但这两种类型的 θ 活动之间仍然存在显著的相关性。这表明，在反映“警报”信号的抑制相关神经生理活动比例中，类似于静息动态的方面是明显的，其功能是处理和指示需要认知控制。因此，当需要认知控制时，与任务相关的θ 功率的特定方面可能会建立在静息态θ 活动的基础上。
