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[尼卡地平治疗缺血性心脏病患者的特点]

[Characteristics of nicardipine treatment of patients with ischemic heart disease].

作者信息

Zharov E I, Makarovskiĭ V V, Styrova T K, Galichenko I V, Barinov V G, Martynov A I, Vertkin A L

出版信息

Kardiologiia. 1991 Mar;31(3):16-8.

PMID:1875588
Abstract

The new calcium antagonist nicardipine (barizine) was tested for effects on platelet function and transient myocardial ischemia in 23 patients with coronary heart disease. Prior to the therapy, lower platelet function was more frequently encountered in patients with more severe angina pectoris and more prolonged myocardial ischemia. The efficacy of nicardipine was demonstrated to be related to the clinical course of coronary heart disease and the baseline platelet function. It is advisable to prescribe the drug to patients with Functional Class II stable angina and higher platelet functional activity.

摘要

对23例冠心病患者进行了新型钙拮抗剂尼卡地平(苄氮嗪)对血小板功能及短暂性心肌缺血影响的测试。治疗前,更严重心绞痛和更长时间心肌缺血的患者中血小板功能较低的情况更为常见。尼卡地平的疗效被证明与冠心病的临床病程及基线血小板功能有关。建议将该药物开给稳定型II级心绞痛且血小板功能活性较高的患者。

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