Roushan Nader, Zali Fateme, Abtahi Hamidreza, Asadi Mehrnaz, Taslimi Reza, Aletaha Najme
1. Assistant Professor, Department of Internal Medicine, Division of Gastroenterology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2. Resident of Gastroenterology, Imam Khomeini Hospital, Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences.
Med J Islam Repub Iran. 2014 May 7;28:30. eCollection 2014.
Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago.
One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastroduodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria.
81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155).
Based on our findings, SM exposure seems not to be associated with increased esophagitis.
背景 硫芥(SM)对皮肤和黏膜表面有急性和慢性影响。本研究的目的是评估近25年前在伊朗 - 伊拉克战争中接触过SM的退伍军人历史队列中食管炎的发生率。
102例有消化不良和/或烧心症状的退伍军人接受了食管 - 胃十二指肠镜检查。其中,52例曾接触过SM并患有慢性芥子气肺病。对照组包括50例未接触过SM的退伍军人。食管炎根据标准标准进行定义。
81.6%的病例和70.6%的对照组有烧心和/或反流(p = 0.224)。40%的病例和26.5%的对照组出现食管炎(p = 0.155)。
根据我们的研究结果,接触SM似乎与食管炎发生率增加无关。