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普通人群双胞胎样本中饮酒模式的遗传:I. 饮酒量/饮酒频率数据的多维标度分析

The inheritance of alcohol consumption patterns in a general population twin sample: I. Multidimensional scaling of quantity/frequency data.

作者信息

Heath A C, Meyer J, Eaves L J, Martin N G

机构信息

Department of Human Genetics, Medical College of Virginia, Richmond 23298-0033.

出版信息

J Stud Alcohol. 1991 Jul;52(4):345-52. doi: 10.15288/jsa.1991.52.345.

Abstract

Quantity/frequency data on alcohol consumption were obtained by mailed questionnaire from 2,903 same-sex monozygotic and dizygotic Australian twin pairs. Nonmetric multidimensional scaling was applied to these data. A three-dimensional solution was required to account for the observed pattern of twin concordances for alcohol consumption. These results suggest separate determination of abstinence, frequency of consumption and quantity consumed when drinking, rather than inheritance of a single continuum of overall consumption level.

摘要

通过邮寄问卷从2903对澳大利亚同性同卵和异卵双胞胎中获取了酒精消费的数量/频率数据。对这些数据应用了非度量多维标度法。需要一个三维解决方案来解释观察到的双胞胎酒精消费一致性模式。这些结果表明,应分别确定戒酒情况、饮酒频率和饮酒量,而不是单一连续总体消费水平的遗传。

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